HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity. - Wikidata - awgldk - TriplyDB

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity.

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity.

http://www.wikidata.org/entity/Q35757997

about

The Hedgehog protein family A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2 Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro Osteopontin-A Master Regulator of Epithelial-Mesenchymal Transition Cancer Stem Cell Hierarchy in Glioblastoma Multiforme Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets Glioma Stem Cells: Signaling, Microenvironment, and Therapy Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy Common stemness regulators of embryonic and cancer stem cells Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic Signaling The Role of Hedgehog Signaling in Tumor Induced Bone Disease Hedgehog Signaling in the Maintenance of Cancer Stem Cells Hedgehog Signaling in Malignant Pleural Mesothelioma Twisted tango: brain tumor neurovascular interactions A comparative review of canine and human rhabdomyosarcoma with emphasis on classification and pathogenesis Cancer microenvironment, inflammation and cancer stem cells: A hypothesis for a paradigm change and new targets in cancer control Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Brain tumor stem cells: Molecular characteristics and their impact on therapy Targeting glioma stem cells: a novel framework for brain tumors Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy Sonic Hedgehog promotes tumor cell survival by inhibiting CDON pro-apoptotic activity In vitro models of cancer stem cells and clinical applications Glioblastoma Stem-Like Cells: Characteristics, Microenvironment, and Therapy Molecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cells Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma Hedgehog signaling and the Gli code in stem cells, cancer, and metastases Sustained proliferation in cancer: Mechanisms and novel therapeutic targets T cells enhance stem-like properties and conditional malignancy in gliomas Holoclone forming cells from pancreatic cancer cells enrich tumor initiating cells and represent a novel model for study of cancer stem cells Structural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancer Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926 DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance Overcoming therapeutic resistance in glioblastoma: the way forward Inflammation and Gliomagenesis: Bi-Directional Communication at Early and Late Stages of Tumor Progression.Notch inhibitors as a new tool in the war on cancer: a pathway to watch.Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity.An overview of the role of cancer stem cells in spine tumors with a special focus on chordoma.Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy

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P2860

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity.

http://www.wikidata.org/entity/Q35757997

description

2006 nî lūn-bûn

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HEDGEHOG-GLI1 signaling regula ...... f-renewal, and tumorigenicity.

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HEDGEHOG-GLI1 signaling regula ...... f-renewal, and tumorigenicity.

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HEDGEHOG-GLI1 signaling regula ...... f-renewal, and tumorigenicity.

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HEDGEHOG-GLI1 signaling regula ...... f-renewal, and tumorigenicity.

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HEDGEHOG-GLI1 signaling regula ...... f-renewal, and tumorigenicity.

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HEDGEHOG-GLI1 signaling regula ...... f-renewal, and tumorigenicity.

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J.CUB.2006.11.033

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Current Biology

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HEDGEHOG-GLI1 signaling regula ...... f-renewal, and tumorigenicity.

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Ariel Ruiz i Altaba

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Ivan Radovanovic

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Nicolas de Tribolet

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Pilar Sanchez

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Virginie Clement

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P2860

Cancerous stem cells can arise from pediatric brain tumors

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

Identification of human brain tumour initiating cells

Identification of a cancer stem cell in human brain tumors

Patched and smoothened mRNA expression in human astrocytic tumors inversely correlates with histological malignancy

Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

Identification of an amplified, highly expressed gene in a human glioma

Dissecting self-renewal in stem cells with RNA interference

Sonic hedgehog regulates the growth and patterning of the cerebellum

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