Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development
about
An Overview of Genome Organization and How We Got There: from FISH to Hi-CFetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathiesCTCF: an architectural protein bridging genome topology and functionDNA modifications: function and applications in normal and disease StatesCTCF: the protein, the binding partners, the binding sites and their chromatin loopsGlobal genetic architecture of an erythroid quantitative trait locus, HMIP-2r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing dataBasic4Cseq: an R/Bioconductor package for analyzing 4C-seq data.GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data.Role of LDB1 in the transition from chromatin looping to transcription activation.Hydroxyurea treatment in β-thalassemia patients: to respond or not to respond?Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activationThree-dimensional genome architecture: players and mechanisms.Multiplexed chromosome conformation capture sequencing for rapid genome-scale high-resolution detection of long-range chromatin interactions.Revisiting higher-order and large-scale chromatin organizationPre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions.Uncovering enhancer functions using the α-globin locus.Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms.Retroviruses hijack chromatin loops to drive oncogene expression and highlight the chromatin architecture around proto-oncogenic loci.MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region.A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis.Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2CβAn ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB geneThe DEK Oncoprotein Is a Critical Component of the EKLF/KLF1 Enhancer in Erythroid Cells.Unbiased Interrogation of 3D Genome Topology Using Chromosome Conformation Capture Coupled to High-Throughput Sequencing (4C-Seq).Three murine leukemia virus integration regions within 100 kilobases upstream of c-myb are proximal to the 5' regulatory region of the gene through DNA looping.Control of developmentally primed erythroid genes by combinatorial co-repressor actionsThe switch from fetal to adult hemoglobinDisruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model.Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions.In vivo live imaging of RNA polymerase II transcription factories in primary cells.Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation.Ldb1 regulates carbonic anhydrase 1 during erythroid differentiation.Distal regulation of c-myb expression during IL-6-induced differentiation in murine myeloid progenitor M1 cells.Ldb1 complexes: the new master regulators of erythroid gene transcription.Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia.Adenoid cystic carcinoma: emerging role of translocations and gene fusionsTranscription regulation by distal enhancers: who's in the loop?EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination.
P2860
Q26801741-12F61CB1-7113-414C-A13B-04DCD8711E55Q26822810-63092CCF-B7E4-4190-9DA1-50990F07449BQ26823453-9A07271B-92EE-4AF9-A5EB-DFD51D6930EDQ26829214-39723028-BFB8-436E-87AD-A362161B2818Q27028081-F5C03FAF-0E2C-4E43-BF12-E24EF318EC56Q28651652-A647739F-7164-4968-9C56-57DE19999E37Q30625699-802601EC-5BCF-41ED-AA16-E807E5A5911DQ30839765-9344B239-881D-4EC1-AE67-14E2D6FBEED0Q31024668-7964C24E-7F23-4F96-8987-56A733D9134EQ33789575-9CB36864-F37B-4AB2-ABBA-50C398D50E24Q34322542-F52B4889-F026-4FB3-A018-81B691AB8D62Q34348069-704AD2AA-190C-4747-AE60-B10CC05F5F43Q34466522-67A062EA-5068-4309-88E8-E71D6DB95C3CQ34587822-E67BBA8E-F5D0-4406-B344-582E3412D7BAQ34637040-338208B7-D9D6-45B6-95EC-B0314B396F5CQ35099409-D646838D-AA11-43E9-99D6-FFCA3E13134DQ35351225-C802158C-A653-4660-90C6-E15108F766E2Q35407362-66C7D2C8-475A-49BD-BC1E-B85F5F367328Q35584064-09ED4961-826F-4387-8A80-54A2A16DA145Q35597624-15206243-4E36-43AE-A163-184273ACE47AQ35801800-4446E361-166E-40D7-AB29-0508E7962BC5Q35939797-73D1943C-286C-4D24-8A40-14091F0BA312Q36064635-330660C1-622E-4E18-BC10-2794018E441DQ36107006-4E37144C-605F-45B4-85B1-C1F4A23AEEA9Q36109366-0EE2AC97-6793-41C7-86EB-CAE6E019BD13Q36189043-95CC6698-CC4A-4CF4-81E4-56ECA8DBE9A0Q36276479-34E54680-3666-4363-8812-AB0187B214F3Q36358111-50BFE2C3-AE88-4083-B817-0D7CD4FDF68FQ36488272-1B2626E0-5FFF-40CE-8E2C-2EBD17B69C36Q36759840-CF3E1E96-85BC-4299-BEA9-AE33FA981E18Q36800430-7A92050E-E444-4C78-BC0F-DF567D4F2084Q36804109-9FCF7710-C4BC-48DE-A8BC-CE86516E2F77Q36889747-B6ECE6EA-1E7F-41B7-BCD6-D12250DF018DQ37038920-A94BCD67-C27F-4B91-B97D-9C2750BDC484Q37330867-EA03FA27-7370-4551-AD2C-0F7BFB00B754Q37439551-B8451178-4509-40D3-8745-603020689CE3Q37517470-33B11AC6-1C5D-4D13-BB4A-981DF88B0C3DQ37662396-5614FF78-261B-4F46-92E5-4BF220F5F7A1Q38024615-7EAD94D4-FDD4-47D4-87C0-4AEAE7BC42B2Q38054642-F1500AD0-9C0C-4B6E-9CE8-CBA95E8F5FD0
P2860
Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Dynamic long-range chromatin i ...... n during erythroid development
@ast
Dynamic long-range chromatin i ...... n during erythroid development
@en
type
label
Dynamic long-range chromatin i ...... n during erythroid development
@ast
Dynamic long-range chromatin i ...... n during erythroid development
@en
prefLabel
Dynamic long-range chromatin i ...... n during erythroid development
@ast
Dynamic long-range chromatin i ...... n during erythroid development
@en
P2093
P2860
P50
P356
P1433
P1476
Dynamic long-range chromatin i ...... n during erythroid development
@en
P2093
Anita van den Heuvel
Antoine van der Sloot
Charlotte Andrieu-Soler
Ernie de Boer
Frank Grosveld
Jan Christian Bryne
Mary Stevens
Mirjam van den Hout
Robert-Jan Palstra
P2860
P304
P356
10.1038/EMBOJ.2011.450
P407
P577
2011-12-13T00:00:00Z