Self-reactive human CD4 T cell clones form unusual immunological synapses - Wikidata - awgldk - TriplyDB

Self-reactive human CD4 T cell clones form unusual immunological synapses

Self-reactive human CD4 T cell clones form unusual immunological synapses

http://www.wikidata.org/entity/Q35760826

about

A functional framework for interpretation of genetic associations in T1D Antigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.CD6 as a therapeutic target in autoimmune diseases: successes and challenges.Progression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spread T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice.Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells.Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain.The dynamic lives of T cells: new approaches and themes PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis Analysis, Isolation, and Activation of Antigen-Specific CD4(+) and CD8(+) T Cells by Soluble MHC-Peptide Complexes.CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L.Tolerogenic vaccines for Multiple sclerosis Low-affinity CD4+ T cells are major responders in the primary immune response Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse.T-cell trafficking in the central nervous system.Structural basis for self-recognition by autoimmune T-cell receptors.The multiple origins of Type 1 diabetes.The actin-driven spatiotemporal organization of T-cell signaling at the system scale.Kupfer-type immunological synapses in vivo: Raison D'être of SMAC.Cellular imaging in rheumatic diseases.Taming the TCR: antigen-specific immunotherapeutic agents for autoimmune diseases.The Immune Synapse: Past, Present, and Future.T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology.Studying Dynamic Plasma Membrane Binding of TCR-CD3 Chains During Immunological Synapse Formation Using Donor-Quenching FRET and FLIM-FRET.The integration of signaling and the spatial organization of the T cell synapse."Cell biology meets physiology: functional organization of vertebrate plasma membranes"--the immunological synapse.NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease.Autoreactive T cells in type 1 diabetes.Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex.Analyzing Actin Dynamics at the Immunological Synapse.A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity.The immunological synapse Heterogeneity of circulating CD8 T-cells specific to islet, neo-antigen and virus in patients with type 1 diabetes mellitus

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Self-reactive human CD4 T cell clones form unusual immunological synapses

http://www.wikidata.org/entity/Q35760826

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Self-reactive human CD4 T cell clones form unusual immunological synapses

@ast

Self-reactive human CD4 T cell clones form unusual immunological synapses

@en

type

label

Self-reactive human CD4 T cell clones form unusual immunological synapses

@ast

Self-reactive human CD4 T cell clones form unusual immunological synapses

@en

prefLabel

Self-reactive human CD4 T cell clones form unusual immunological synapses

@ast

Self-reactive human CD4 T cell clones form unusual immunological synapses

@en

P1433

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P1433

Journal of Experimental Medicine

P1476

Self-reactive human CD4 T cell clones form unusual immunological synapses

@en

P2093

David A Schubert

http://www.w3.org/2001/XMLSchema#string

Dhruv K Sethi

http://www.w3.org/2001/XMLSchema#string

Etienne Gagnon

http://www.w3.org/2001/XMLSchema#string

Helena Reijonen

http://www.w3.org/2001/XMLSchema#string

Joseph J Sabatino

http://www.w3.org/2001/XMLSchema#string

Kai W Wucherpfennig

http://www.w3.org/2001/XMLSchema#string

Nilufer P Seth

http://www.w3.org/2001/XMLSchema#string

Susana Gordo

http://www.w3.org/2001/XMLSchema#string

P2860

A single class II myosin modulates T cell motility and stopping, but not synapse formation

Small molecules that enhance the catalytic efficiency of HLA-DM

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.

Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers

Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au

Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'

A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

The immunological synapse: a molecular machine controlling T cell activation

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335-352

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scholarly article

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10.1084/JEM.20111485

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P433

2

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209

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Brian D Evavold

Michael L Dustin

Santosh Vardhana

Kaushik Choudhuri

P577

2012-02-06T00:00:00Z

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221812447

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22312112

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3280872

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