Transporter-mediated Efflux Influences CNS Side Effects: ABCB1, from Antitarget to Target.
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ChemProt: a disease chemical biology databaseInternational Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsAnalysis of in vitro bioactivity data extracted from drug discovery literature and patents: Ranking 1654 human protein targets by assayed compounds and molecular scaffoldsA novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fieldsImproving the prediction of the brain disposition for orally administered drugs using BDDCS.Linking pharmacology to clinical reports: cyclobenzaprine and its possible association with serotonin syndromeFull efficacy with no CNS side-effects: unachievable panacea or reality? DMPK considerations in design of drugs with limited brain penetration.Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design.Toward a unifying strategy for the structure-based prediction of toxicological endpoints.Use of shape similarities for the classification of P-glycoprotein substrates and nonsubstrates.Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA.Cross-pharmacology analysis of G protein-coupled receptorsDiphenhydramine as a selective probe to study H+-antiporter function at the blood-brain barrier: Application to [11C]diphenhydramine positron emission tomography imaging.Brain histamine H1 receptor occupancy measured by PET after oral administration of levocetirizine, a non-sedating antihistamine.Understanding drug-likeness
P2860
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P2860
Transporter-mediated Efflux Influences CNS Side Effects: ABCB1, from Antitarget to Target.
description
2010 nî lūn-bûn
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
@zh-hk
2010年論文
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2010年論文
@zh-tw
2010年论文
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name
Transporter-mediated Efflux In ...... B1, from Antitarget to Target.
@ast
Transporter-mediated Efflux In ...... B1, from Antitarget to Target.
@en
type
label
Transporter-mediated Efflux In ...... B1, from Antitarget to Target.
@ast
Transporter-mediated Efflux In ...... B1, from Antitarget to Target.
@en
prefLabel
Transporter-mediated Efflux In ...... B1, from Antitarget to Target.
@ast
Transporter-mediated Efflux In ...... B1, from Antitarget to Target.
@en
P2860
P356
P1476
Transporter-mediated Efflux In ...... B1, from Antitarget to Target.
@en
P2093
Emanuele Carosati
Fabio Broccatelli
P2860
P356
10.1002/MINF.200900075
P577
2010-01-01T00:00:00Z