Targeted delivery of proteins across the blood-brain barrier.
about
A carrier for non-covalent delivery of functional beta-galactosidase and antibodies against amyloid plaques and IgM to the brainNeuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model.Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brainPeripheral delivery of a CNS targeted, metalo-protease reduces aβ toxicity in a mouse model of Alzheimer's diseaseNon-Viral Nucleic Acid Delivery Strategies to the Central Nervous SystemGetting into the brain: liposome-based strategies for effective drug delivery across the blood-brain barrierBlood brain barrier: the role of calcium homeostasis.ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.Immunohistochemical detection of transgene expression in the brain using small epitope tags.Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cellsGenetic approach for intracerebroventricular delivery.Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma.A neuroprotective brain-penetrating endopeptidase fusion protein ameliorates Alzheimer disease pathology and restores neurogenesis.Targeting eNOS and beyond: emerging heterogeneity of the role of endothelial Rho proteins in stroke protectionTherapeutic approaches for lysosomal storage diseasesKinetic and dynamic computational model-based characterization of new proteins in mice: application to interferon alpha linked to apolipoprotein A-I.Setting-up an in vitro model of rat blood-brain barrier (BBB): a focus on BBB impermeability and receptor-mediated transportNeuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds.Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models.Human-derived physiological heat shock protein 27 complex protects brain after focal cerebral ischemia in mice.Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier.Large-volume intrathecal enzyme delivery increases survival of a mouse model of late infantile neuronal ceroid lipofuscinosis.Specific amyloid β clearance by a catalytic antibody construct.Engineered antibody therapies coming of age for aging brainsFrom the liver to the brain across the blood-brain barrier.Glioblastoma multiforme: novel therapeutic approachesEngaging neuroscience to advance translational research in brain barrier biology.A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy.Phage display as a tool to discover blood-brain barrier (BBB)-shuttle peptides: panning against a human BBB cellular model.Ratio of apoB/LDL: a potential clinical index for vascular cognitive impairmentSystemic Central Nervous System (CNS)-targeted Delivery of Neuropeptide Y (NPY) Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer Disease.Neurometabolic roles of ApoE and Ldl-R in mouse brainEngineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrierTargeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration.The final frontier -- crossing the blood-brain barrier.A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA.Targeting of the CNS in MPS-IH using a nonviral transferrin-alpha-L-iduronidase fusion gene product.Novel strategies for Alzheimer's disease treatment.Targeting receptor-mediated transport for delivery of biologics across the blood-brain barrier.Therapy for prion diseases: Insights from the use of RNA interference.
P2860
Q27311201-D5CCD409-4414-4BFC-9CC5-FAFA98384CC9Q27316651-381A9202-30A9-495E-8FCC-AA5E8A7CB98CQ27331875-EDEAAFFA-7EFE-4F7A-AB48-A9EB661DB797Q27437619-6E88D911-23EC-46F3-BB77-624BBA9C8925Q28068242-37ED7039-6B24-4EDD-B794-49C2A03150E9Q28071873-490D33A3-2358-4672-8C07-3FB1DFAF93F6Q30436341-254B810F-9EE9-4738-AEE1-AD4724D5E60AQ30650119-CDA1EA7B-A816-478A-9DD2-DF0C04061B46Q33532297-E51A4312-ADCF-45EA-9092-6F48030C2BD1Q33584151-A93221DB-DE17-4A6F-99A8-694CD2D6C2D7Q33732849-C1FDBED9-0800-4743-8AB6-FC630D962948Q33779928-D01E0035-2FF2-442C-A7A0-CFB0949B6E25Q33793059-2D60A165-DF9F-4BAA-9374-7AE9ACEA1BF2Q34088803-480454B3-C0D6-43AA-92E7-D6E1EDAA9F49Q34311420-7D5DEAE0-30DE-4556-9800-59DC83A84994Q34359523-AE822119-EA1A-45F6-AF6D-8BBC0A25FA9FQ34400993-EE7C7F3C-3422-49D5-81C6-292574F1E77DQ34464236-FE4352C4-1C29-40EC-887A-8206F05578EEQ34560712-1873288F-2507-4393-9E2A-AA5AE7A1DFF4Q34778800-57BB018C-3437-4102-993C-001F3D3380D8Q35034401-90BEDD79-75F3-4627-8245-45E4E5587EC3Q35285680-53B670BC-5F5E-4939-A24F-623854B3ED76Q35451085-BC10B26C-0FEB-4D28-9CA0-2B338256B918Q35596571-FCF8ED71-E057-40F2-958D-42319B61906FQ35778166-CAC658F1-B606-4724-B543-61190C9C9415Q35825491-8438BF9F-565F-4F1C-91E3-229598F35109Q35909313-94F5A60C-E8AC-45AB-9440-ABF6603EDB91Q36086721-5CE3CA6B-8E07-4FEC-A891-9B3C729D816AQ36093633-BB07A84B-CC40-4327-8517-921F840D9D1BQ36204147-AD7B315D-CFC6-400E-81E9-D7C8494E08AFQ36489317-0505EE9D-1792-4E9D-83D5-CDC5BE61C7C9Q36522825-A8B0A3F3-4D8D-441D-BFC9-803658356C60Q36637219-232DF879-D809-4015-9F5E-C814183B060FQ36658903-388CE9F9-19EB-40C4-B150-281CDD1ADCD3Q36870076-B1D55C88-0F98-4EC3-B0D6-171320991EECQ36870087-7F5CE33D-687D-4219-ABCA-47C44AC99C01Q36953167-4A826258-EA3F-47B6-B2C4-B7AADEA5DE66Q37012066-E6C9EBC3-6BAA-4BF2-9C99-DA58E1E509C9Q37312010-F2AC85CF-BA4C-4CB2-A0A4-C52CED85EF1FQ37549830-E7554B17-AC56-4A77-B2EF-29C54AB923C9
P2860
Targeted delivery of proteins across the blood-brain barrier.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Targeted delivery of proteins across the blood-brain barrier.
@ast
Targeted delivery of proteins across the blood-brain barrier.
@en
type
label
Targeted delivery of proteins across the blood-brain barrier.
@ast
Targeted delivery of proteins across the blood-brain barrier.
@en
prefLabel
Targeted delivery of proteins across the blood-brain barrier.
@ast
Targeted delivery of proteins across the blood-brain barrier.
@en
P2860
P356
P1476
Targeted delivery of proteins across the blood-brain barrier.
@en
P2093
Brian J Spencer
Inder M Verma
P2860
P304
P356
10.1073/PNAS.0702170104
P407
P577
2007-04-26T00:00:00Z