Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV.
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Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-αRationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategyTumor stroma as targets for cancer therapyFibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites.Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease.Cancer-associated fibroblasts are positively correlated with metastatic potential of human gastric cancers.Pharmacokinetics and toxicology of a fibroblast activation protein (FAP)-activated prodrug in murine xenograft models of human cancer.Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse modelColon cancer molecular subtypes identified by expression profiling and associated to stroma, mucinous type and different clinical behavior.Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activationFibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterationsTargeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug.Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell behavior.Circulating FGF21 proteolytic processing mediated by fibroblast activation protein.Interstitial collagen catabolism.Targeting inhibition of fibroblast activation protein-α and prolyl oligopeptidase activities on cells common to metastatic tumor microenvironmentsFibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice.Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells.Inhibitor of DASH proteases affects expression of adhesion molecules in osteoclasts and reduces myeloma growth and bone disease.Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers.Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice.The road to integrative cancer therapies: emergence of a tumor-associated fibroblast protease as a potential therapeutic target in cancer.Invading one step at a time: the role of invadopodia in tumor metastasis.Fibroblast activation protein: A potential therapeutic target in cancer.Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?The expression of proline-specific enzymes in the human lungSuppression of tumor growth in mice by rationally designed pseudopeptide inhibitors of fibroblast activation protein and prolyl oligopeptidase.Extracellular molecules in hematopoietic stem cell mobilisation.Tumor Microenvironment, a Paradigm in Hepatocellular Carcinoma Progression and Therapy.Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions.Expression and role of the cell surface protease seprase/fibroblast activation protein-α (FAP-α) in astroglial tumors.Inhibition of fibroblast activation protein and dipeptidylpeptidase 4 increases cartilage invasion by rheumatoid arthritis synovial fibroblasts.Fibroblast activation protein-α promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathways.Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma.Circulating fibroblast activation protein and dipeptidyl peptidase 4 in rheumatoid arthritis and systemic sclerosis.Evaluation of the radiolabeled boronic acid-based FAP inhibitor MIP-1232 for atherosclerotic plaque imaging.
P2860
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P2860
Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Effect of fibroblast activatio ...... collagen types I, III, and IV.
@ast
Effect of fibroblast activatio ...... collagen types I, III, and IV.
@en
type
label
Effect of fibroblast activatio ...... collagen types I, III, and IV.
@ast
Effect of fibroblast activatio ...... collagen types I, III, and IV.
@en
prefLabel
Effect of fibroblast activatio ...... collagen types I, III, and IV.
@ast
Effect of fibroblast activatio ...... collagen types I, III, and IV.
@en
P2093
P2860
P1476
Effect of fibroblast activatio ...... collagen types I, III, and IV.
@en
P2093
Kenneth W Jackson
Kyung N Lee
Patrick A McKee
Victoria J Christiansen
P2860
P304
P356
10.1016/J.ABB.2006.11.006
P407
P577
2006-11-17T00:00:00Z