Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. - Wikidata - awgldk - TriplyDB

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

http://www.wikidata.org/entity/Q35764323

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Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins Complex interactions between the laminin alpha 4 subunit and integrins regulate endothelial cell behavior in vitro and angiogenesis in vivo.Tumor-selective response to antibody-mediated targeting of alphavbeta3 integrin in ovarian cancer The role of alpha(v)beta(3) in prostate cancer progression Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis Recent translational research: antiangiogenic therapy for breast cancer - where do we stand?Breast cancer-induced angiogenesis: multiple mechanisms and the role of the microenvironment Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD Anti-angiogenic alternatives to VEGF blockade αV integrins in angiogenesis and cancer Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains Retroviral delivery of homeobox D3 gene induces cerebral angiogenesis in mice cis Interaction of the cell adhesion molecule CEACAM1 with integrin beta(3)Human bladder cancer invasion model using rat bladder in vitro and its use to test mechanisms and therapeutic inhibitors of invasion NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli Cell contact-dependent activation of alpha3beta1 integrin modulates endothelial cell responses to thrombospondin-1 Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities Integrins in cancer: biological implications and therapeutic opportunities Ultrasound molecular imaging of tumor angiogenesis with an integrin targeted microbubble contrast agent.Ultrasonic analysis of peptide- and antibody-targeted microbubble contrast agents for molecular imaging of alphavbeta3-expressing cells.18F-labeled galacto and PEGylated RGD dimers for PET imaging of αvβ3 integrin expression.Molecular cloning and characterization of antigens expressed on rat tumor vascular endothelial cells.Specialization of tumour vasculature.Inhibition of experimental choroidal neovascularization in rats by an alpha(v)-integrin antagonist.A novel peptide isolated from a phage display library inhibits tumor growth and metastasis by blocking the binding of vascular endothelial growth factor to its kinase domain receptor.Disease-modifying activity of SB 273005, an orally active, nonpeptide alphavbeta3 (vitronectin receptor) antagonist, in rat adjuvant-induced arthritis.A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries.Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb.CC-PLA2-1 and CC-PLA2-2, two Cerastes cerastes venom-derived phospholipases A2, inhibit angiogenesis both in vitro and in vivo.Clinical significance of angiogenic factors in breast cancer.Integrins as "functional hubs" in the regulation of pathological angiogenesis Angiogenesis in urological malignancy: prognostic indicator and therapeutic target.The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.N-myc downstream-regulated gene 1 inhibits the proliferation and invasion of hepatocellular carcinoma cells via the regulation of integrin β3 A role for angiogenesis in rheumatoid arthritis.Dissection of platelet and myeloid cell defects by conditional targeting of the beta3-integrin subunit.

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P2860

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

http://www.wikidata.org/entity/Q35764323

description

1995 nî lūn-bûn

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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1995年论文

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1995年论文

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name

Antiintegrin alpha v beta 3 bl ...... nd angiogenesis in human skin.

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Antiintegrin alpha v beta 3 bl ...... nd angiogenesis in human skin.

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type

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Antiintegrin alpha v beta 3 bl ...... nd angiogenesis in human skin.

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Antiintegrin alpha v beta 3 bl ...... nd angiogenesis in human skin.

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prefLabel

Antiintegrin alpha v beta 3 bl ...... nd angiogenesis in human skin.

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Antiintegrin alpha v beta 3 bl ...... nd angiogenesis in human skin.

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Journal of Clinical Investigation

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Antiintegrin alpha v beta 3 bl ...... nd angiogenesis in human skin.

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P2093

D A Cheresh

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D Visscher

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F H Sarkar

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P C Brooks

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R Klemke

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S Strömblad

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P2860

Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Requirement of vascular integrin alpha v beta 3 for angiogenesis

Human/severe combined immunodeficient mouse chimeras. An experimental in vivo model system to study the regulation of human endothelial cell-leukocyte adhesion molecules.

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells

The role of angiogenesis in tumor growth.

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma.

Capillary growth: a two-cell system.

Growth and invasion of human melanomas in human skin grafted to immunodeficient mice

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases.

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1815-1822

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10.1172/JCI118227

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4

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96

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15639191

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7560073

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185818

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