Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis
about
Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiationRoles of microRNAs in prenatal chondrogenesis, postnatal chondrogenesis and cartilage-related diseasesEpigenetics advancing personalized nanomedicine in cancer therapyIncreased DNA Methylation and Reduced Expression of Transcription Factors in Human Osteoarthritis Cartilage.The role of DNA methylation in common skeletal disordersSignificance of epigenetic landscape in cartilage regeneration from the cartilage development and pathology perspective.Decrease of miR-195 Promotes Chondrocytes Proliferation and Maintenance of Chondrogenic Phenotype via Targeting FGF-18 PathwayMicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes.p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis.Articular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis.Recent progress in osteoarthritis research.Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cellsTGF-β signaling and the development of osteoarthritisEmerging targets in osteoarthritis therapy.LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes.MicroRNA Levels as Prognostic Markers for the Differentiation Potential of Human Mesenchymal Stromal Cell DonorsChondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis.Attenuation of the progression of articular cartilage degeneration by inhibition of TGF-β1 signaling in a mouse model of osteoarthritismiR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes.Identification of differentially methylated regions in new genes associated with knee osteoarthritis.Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis.Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.RNA Interference Mediated Interleukin-1β Silencing in Inflamed Chondrocytes Decreases Target and Downstream Catabolic Responses.Mechanical and IL-1β Responsive miR-365 Contributes to Osteoarthritis Development by Targeting Histone Deacetylase 4.MicroRNA functions in osteogenesis and dysfunctions in osteoporosisPhlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis.MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis.Epigenetic and microRNA regulation during osteoarthritis developmentEnhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis.Inflammation and epigenetic regulation in osteoarthritis.Epigenetics in osteoarthritis and its implication for future therapeutics.Perspectives on epigenetic-based immune intervention for rheumatic diseases.Review: the role of microRNAs in osteoarthritis and chondrogenesis.Advances and challenges in gene-based approaches for osteoarthritis.The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments?Epigenetic-based immune intervention for rheumatic diseases.Use of tissue engineering strategies to repair joint tissues in osteoarthritis: viral gene transfer approaches.MicroRNAs are potential prognostic and therapeutic targets in diabetic osteoarthritis.Cartilage tissue engineering: recent advances and perspectives from gene regulation/therapy.The Disease-Modifying Effects of Hyaluronan in the Osteoarthritic Disease State
P2860
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P2860
Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Epigenomic and microRNA-mediat ...... omeostasis, and osteoarthritis
@ast
Epigenomic and microRNA-mediat ...... omeostasis, and osteoarthritis
@en
type
label
Epigenomic and microRNA-mediat ...... omeostasis, and osteoarthritis
@ast
Epigenomic and microRNA-mediat ...... omeostasis, and osteoarthritis
@en
prefLabel
Epigenomic and microRNA-mediat ...... omeostasis, and osteoarthritis
@ast
Epigenomic and microRNA-mediat ...... omeostasis, and osteoarthritis
@en
P2860
P1476
Epigenomic and microRNA-mediat ...... omeostasis, and osteoarthritis
@en
P2093
Kenneth B Marcu
Mary B Goldring
P2860
P304
P356
10.1016/J.MOLMED.2011.11.005
P577
2011-12-17T00:00:00Z