Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease.
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NMR Meets Tau: Insights into Its Function and PathologyDeveloping therapeutic approaches to tau, selected kinases, and related neuronal protein targetsTangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemAlzheimer disease: a tale of two prionsCytoskeletal pathologies of Alzheimer diseaseNucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constantsDifferentiating Alzheimer disease-associated aggregates with small molecules.Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer's disease in multiplex immunoassay panels of cerebrospinal fluid.Roles of tau protein in health and disease.A nucleated assembly mechanism of Alzheimer paired helical filaments.Quantitative characterization of heparin binding to Tau protein: implication for inducer-mediated Tau filament formation.Characterization of tau fibrillization in vitro.Tau pathology generated by overexpression of tau.Tau-directed drug discovery for Alzheimer's disease and related tauopathies: a focus on tau assembly inhibitors.Palmitic Acid-BSA enhances Amyloid-β production through GPR40-mediated dual pathways in neuronal cells: Involvement of the Akt/mTOR/HIF-1α and Akt/NF-κB pathwaysThe role of the lipid bilayer in tau aggregationPlasma-free fatty acids, fatty acid-binding protein 4, and mortality in older adults (from the Cardiovascular Health Study).Structure and pathology of tau protein in Alzheimer disease.Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation.Oligomer formation of tau protein hyperphosphorylated in cells.Metabotyping of docosahexaenoic acid - treated Alzheimer's disease cell modelIn vitro aggregation assays using hyperphosphorylated tau protein.Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms.Potentiation of TRPV3 channel function by unsaturated fatty acids.Interaction of tau protein with model lipid membranes induces tau structural compaction and membrane disruption.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease.Tau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies?Effects of diet and behavioral enrichment on free fatty acids in the aged canine brainAssociation between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic studyIdentification of an aggregation-prone structure of tau.Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons.Pseudomonas aeruginosa exoenzymes U and Y induce a transmissible endothelial proteinopathyAminothienopyridazines and methylene blue affect Tau fibrillization via cysteine oxidation.EFhd2 is a novel amyloid protein associated with pathological tau in Alzheimer's disease.Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure.Characteristics of tau oligomers.Tau aggregation in Alzheimer's disease: what role for phosphorylation?Tau-based treatment strategies in neurodegenerative diseasesIdentification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening.
P2860
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P2860
Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Free fatty acids stimulate the ...... enesis in Alzheimer's disease.
@ast
Free fatty acids stimulate the ...... enesis in Alzheimer's disease.
@en
type
label
Free fatty acids stimulate the ...... enesis in Alzheimer's disease.
@ast
Free fatty acids stimulate the ...... enesis in Alzheimer's disease.
@en
prefLabel
Free fatty acids stimulate the ...... enesis in Alzheimer's disease.
@ast
Free fatty acids stimulate the ...... enesis in Alzheimer's disease.
@en
P2860
P1476
Free fatty acids stimulate the ...... genesis in Alzheimer's disease
@en
P2093
D M Wilson
L I Binder
P2860
P304
P407
P577
1997-06-01T00:00:00Z