Specific inhibition of formation of transcription complexes by a calicheamicin oligosaccharide: a paradigm for the development of transcriptional antagonists.
about
Inhibition of gene expression in human cells through small molecule-RNA interactionsSignificance of ligand tails for interaction with the minor groove of B-DNAChemical approaches to control gene expression.Sequence-selective carbohydrate-DNA interaction: dimeric and monomeric forms of the calicheamicin oligosaccharide interfere with transcription factor function.Calicheamicin-DNA complexes: warhead alignment and saccharide recognition of the minor groove.Organic synthesis and cell biology: partners in controlling gene expression.HMG I(Y) interferes with the DNA binding of NF-AT factors and the induction of the interleukin 4 promoter in T cells.Structural and conformational features relevant to the anti-tumor activity of calicheamicin γ 1I.Specific targeting of protein-DNA complexes by DNA-reactive drugs (+)-CC-1065 and pluramycins.
P2860
Q28343697-33415D90-940F-42DA-95DB-A63853D4E128Q28346194-3AACA031-289C-4875-9428-E68234BB305AQ30971784-EB4664B3-6E9C-48D9-92E0-CF5E0E69946BQ33591600-BA47DC69-3316-496B-8878-741FBC009684Q33779886-D084FE00-994C-4D12-B823-70DEF313913DQ35771242-B2FED7F4-8351-497E-9343-5BB30BA51D5DQ37092275-E8729687-7598-47EC-AA2F-79150D2C45EEQ37907992-65BF01F8-DA4E-40D3-B8D4-C7358966E35DQ41172880-A28BE748-A999-4630-A8C4-608F44DB9CAB
P2860
Specific inhibition of formation of transcription complexes by a calicheamicin oligosaccharide: a paradigm for the development of transcriptional antagonists.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Specific inhibition of formati ...... f transcriptional antagonists.
@ast
Specific inhibition of formati ...... f transcriptional antagonists.
@en
type
label
Specific inhibition of formati ...... f transcriptional antagonists.
@ast
Specific inhibition of formati ...... f transcriptional antagonists.
@en
prefLabel
Specific inhibition of formati ...... f transcriptional antagonists.
@ast
Specific inhibition of formati ...... f transcriptional antagonists.
@en
P2093
P2860
P356
P1476
Specific inhibition of formati ...... f transcriptional antagonists.
@en
P2093
G R Crabtree
S J Danishefsky
S L Schreiber
P2860
P304
P356
10.1073/PNAS.91.20.9203
P407
P577
1994-09-01T00:00:00Z