Farnesyltransferase inhibitors reverse taxane resistance
about
The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent mannerTargeting protein prenylation for cancer therapyDirect assessment of P-glycoprotein efflux to determine tumor response to chemotherapy.Aberrant promoter methylation of caveolin-1 is associated with favorable response to taxane-platinum combination chemotherapy in advanced NSCLCRational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancerFarnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies.Self-assembled Tat nanofibers as effective drug carrier and transporter.BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling.Vorinostat increases carboplatin and paclitaxel activity in non-small-cell lung cancer cells.Acetylated tubulin (AT) as a prognostic marker in squamous cell carcinoma of the head and neck.The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells.Phase I study of lonafarnib (SCH66336) in combination with trastuzumab plus paclitaxel in Her2/neu overexpressing breast cancer: EORTC study 16023.
P2860
Q24312194-14D77A35-DD3F-42F6-ABD2-C8933CDB4621Q33679239-523E90AA-3A36-4344-8C93-A0466A830E52Q33814552-667E1630-4435-47FD-8EA7-41FD32F73282Q34183784-3FA53EBE-BBBA-4128-BD18-AF8A84A94AAAQ35079955-06ADE9D7-65E8-4709-9BB9-819881BC4A7AQ35091519-D3798474-D87C-489D-8162-1178A31807B7Q37237907-E721154F-FF06-491A-B4A6-BA73FF6CE6FEQ37396876-883ED932-9E8D-471D-83D5-AC3115E4FF12Q37480658-6773235A-71B3-4788-B85E-323C7A720EE4Q37631283-DB83F00E-C9E1-4BD4-B814-7F60900AD966Q40134426-37BF23EB-46A3-4E83-969D-5DFB1BE88BDFQ54478541-D62083BD-F7A4-4172-B7FA-B55CA2317484
P2860
Farnesyltransferase inhibitors reverse taxane resistance
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Farnesyltransferase inhibitors reverse taxane resistance
@ast
Farnesyltransferase inhibitors reverse taxane resistance
@en
type
label
Farnesyltransferase inhibitors reverse taxane resistance
@ast
Farnesyltransferase inhibitors reverse taxane resistance
@en
prefLabel
Farnesyltransferase inhibitors reverse taxane resistance
@ast
Farnesyltransferase inhibitors reverse taxane resistance
@en
P2093
P2860
P1433
P1476
Farnesyltransferase inhibitors reverse taxane resistance
@en
P2093
Adam I Marcus
Aurora M O'Brate
Fadlo R Khuri
Fernando Díaz
Jose Manuel Andreu
Paraskevi Giannakakou
Ruben M Buey
Shala Thomas
P2860
P304
P356
10.1158/0008-5472.CAN-06-0699
P407
P577
2006-09-01T00:00:00Z