about
Deletion of ultraconserved elements yields viable miceHighly conserved non-coding sequences are associated with vertebrate developmentComparative evolutionary genomics of the HADH2 gene encoding Abeta-binding alcohol dehydrogenase/17beta-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10)Asymmetrical distribution of non-conserved regulatory sequences at PHOX2B is reflected at the ENCODE loci and illuminates a possible genome-wide trendThe sequence and analysis of duplication-rich human chromosome 16The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivatorHistone H3K27ac separates active from poised enhancers and predicts developmental stateUltraconserved cDNA segments in the human transcriptome exhibit resistance to folding and implicate function in translation and alternative splicingUltraconserved elements: analyses of dosage sensitivity, motifs and boundariesABC: software for interactive browsing of genomic multiple sequence alignment dataA model of the statistical power of comparative genome sequence analysisDG-CST (Disease Gene Conserved Sequence Tags), a database of human-mouse conserved elements associated to disease genesArrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomesConservation anchors in the vertebrate genomeHuman-zebrafish non-coding conserved elements act in vivo to regulate transcriptionVariation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy.Decoding the non-coding genome: elucidating genetic risk outside the coding genomeStudy of Modern Human Evolution via Comparative Analysis with the Neanderthal GenomePoint mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactylyIdentification and analysis of a conserved Tcfap2a intronic enhancer element required for expression in facial and limb bud mesenchymeDevelopment of five digits is controlled by a bipartite long-range cis-regulatorAn ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacementIdentification and characterization of lineage-specific genes within the PoaceaePrimate TNF promoters reveal markers of phylogeny and evolution of innate immunityA family of conserved noncoding elements derived from an ancient transposable elementGenome-wide association studies for common diseases and complex traitsIn vivo enhancer analysis of human conserved non-coding sequencesRadiation hybrid mapping of genes and newly identified microsatellites in candidate regions for bovine arthrogryposis-palatoschisis and progressive ataxia based on comparative data from man, mouse and rat.Modeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organizationHuman GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers.CONDOR: a database resource of developmentally associated conserved non-coding elements.Analysis of sequence conservation at nucleotide resolutionSynBlast: assisting the analysis of conserved synteny information.Structural relationships between highly conserved elements and genes in vertebrate genomes.Genomic regions with distinct genomic distance conservation in vertebrate genomes.Lack of association of TIM3 polymorphisms and allergic phenotypes.Differential Gene Expression in the Human Brain Is Associated with Conserved, but Not Accelerated, Noncoding Sequences.Subtree power analysis and species selection for comparative genomicsAnnotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequencesDistinct functional constraints partition sequence conservation in a cis-regulatory element
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Comparative genomics at the vertebrate extremes.
@ast
Comparative genomics at the vertebrate extremes.
@en
type
label
Comparative genomics at the vertebrate extremes.
@ast
Comparative genomics at the vertebrate extremes.
@en
prefLabel
Comparative genomics at the vertebrate extremes.
@ast
Comparative genomics at the vertebrate extremes.
@en
P2860
P356
P1476
Comparative genomics at the vertebrate extremes.
@en
P2093
Dario Boffelli
Marcelo A Nobrega
P2860
P2888
P304
P356
10.1038/NRG1350
P577
2004-06-01T00:00:00Z