Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context.
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Genotyping of human neutrophil antigens (HNA) from whole genome sequencing dataProtein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts3′-Intercalation of a N 2 -dG 1 R - trans - anti -Benzo[ c ]phenanthrene DNA Adduct in an Iterated (CG) 3 RepeatNucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactionsDifferential nucleotide excision repair susceptibility of bulky DNA adducts in different sequence contexts: hierarchies of recognition signalsDNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular ConsequencesDistant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion.Base sequence context effects on nucleotide excision repair.Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA.Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitroTP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.CHEMICAL SELECTIVITY OF NUCLEOBASE ADDUCTION RELATIVE TO IN VIVO MUTATION SITES ON EXON 7 FRAGMENT OF P53 TUMOR SUPPRESSOR GENEAdenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are notThe sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisionsDensity Functional Study of the Influence of C5 Cytosine Substitution in Base Pairs with Guanine.Chemistry and structural biology of DNA damage and biological consequencesC8-linked bulky guanosine DNA adducts: experimental and computational insights into adduct conformational preferences and resulting mutagenicity.(DNS)C: a fluorescent, environmentally sensitive cytidine derivative for the direct detection of GGG triad sequences.Repair-Resistant DNA Lesions.Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair.Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex.
P2860
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P2860
Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context.
description
2007 nî lūn-bûn
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2007年の論文
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2007年論文
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2007年論文
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2007年論文
@zh-hk
2007年論文
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2007年論文
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2007年论文
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2007年论文
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name
Exocyclic amino groups of flan ...... a GG mutation hotspot context.
@ast
Exocyclic amino groups of flan ...... a GG mutation hotspot context.
@en
type
label
Exocyclic amino groups of flan ...... a GG mutation hotspot context.
@ast
Exocyclic amino groups of flan ...... a GG mutation hotspot context.
@en
prefLabel
Exocyclic amino groups of flan ...... a GG mutation hotspot context.
@ast
Exocyclic amino groups of flan ...... a GG mutation hotspot context.
@en
P2093
P2860
P356
P1476
Exocyclic amino groups of flan ...... a GG mutation hotspot context.
@en
P2093
Alexander Kolbanovskiy
Dinshaw J Patel
Fabián A Rodríguez
Nicholas E Geacintov
Shantu Amin
Suse Broyde
Yijin Tang
P2860
P304
P356
10.1093/NAR/GKM022
P407
P577
2007-02-07T00:00:00Z