Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication.
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The hope for an HIV vaccine based on induction of CD8+ T lymphocytes--a reviewImmunogenicity of seven new recombinant yellow fever viruses 17D expressing fragments of SIVmac239 Gag, Nef, and Vif in Indian rhesus macaquesEx vivo SIV-specific CD8 T cell responses in heterozygous animals are primarily directed against peptides presented by a single MHC haplotypeGagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivoKinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infectionsControl of viremia and prevention of AIDS following immunotherapy of SIV-infected macaques with peptide-pulsed bloodImplications of CTL-mediated killing of HIV-infected cells during the non-productive stage of infectionInfluence of HAART on alternative reading frame immune responses over the course of HIV-1 infectionInhibitory potential of subpopulations of CD8+ T cells in HIV-1-infected elite suppressorsAltered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques.CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.Allogeneic lymphocytes persist and traffic in feral MHC-matched mauritian cynomolgus macaquesPhylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titersTwo MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity.Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic.Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.Unexpected diversity of cellular immune responses against Nef and Vif in HIV-1-infected patients who spontaneously control viral replicationIn situ detection of Gag-specific CD8+ cells in the GI tract of SIV infected Rhesus macaques.Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle SanctuaryT-cell correlates of vaccine efficacy after a heterologous simian immunodeficiency virus challenge.High viremia is associated with high levels of in vivo major histocompatibility complex class I Downregulation in rhesus macaques infected with simian immunodeficiency virus SIVmac239.Trivalent adenovirus type 5 HIV recombinant vaccine primes for modest cytotoxic capacity that is greatest in humans with protective HLA class I alleles.Experimental depletion of CD8+ cells in acutely SIVagm-infected African Green Monkeys results in increased viral replication.Robust, vaccine-induced CD8(+) T lymphocyte response against an out-of-frame epitopeThe role of MHC class I allele Mamu-A*07 during SIV(mac)239 infectionSubdominant/cryptic CD8 T cell epitopes contribute to resistance against experimental infection with a human protozoan parasite.Immunity to HIV in Early LifeResponses against a subdominant CD8+ T cell epitope protect against immunopathology caused by a dominant epitope.Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge.CD8+ T cell recognition of cryptic epitopes is a ubiquitous feature of AIDS virus infectionImpact of MHC class I diversity on immune control of immunodeficiency virus replication.Vaccination with lipid core peptides fails to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria modelMacaque long-term nonprogressors resist superinfection with multiple CD8+ T cell escape variants of simian immunodeficiency virus.Whole genome sequencing of SIV-infected macaques identifies candidate loci that may contribute to host control of virus replicationSimian immunodeficiency virus-specific CD4+ T cells from successful vaccinees target the SIV Gag capsid.A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques.Rapid SIV Env-specific mucosal and serum antibody induction augments cellular immunity in protecting immunized, elite-controller macaques against high dose heterologous SIV challenge.Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques.HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice.
P2860
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P2860
Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Subdominant CD8+ T-cell respon ...... rol of AIDS virus replication.
@ast
Subdominant CD8+ T-cell respon ...... rol of AIDS virus replication.
@en
type
label
Subdominant CD8+ T-cell respon ...... rol of AIDS virus replication.
@ast
Subdominant CD8+ T-cell respon ...... rol of AIDS virus replication.
@en
prefLabel
Subdominant CD8+ T-cell respon ...... rol of AIDS virus replication.
@ast
Subdominant CD8+ T-cell respon ...... rol of AIDS virus replication.
@en
P2093
P2860
P50
P356
P1433
P1476
Subdominant CD8+ T-cell respon ...... rol of AIDS virus replication.
@en
P2093
Benjamin Burwitz
Enrique J León
Eva G Rakasz
Gemma E May
Gnankang Napoe
Jessica R Furlott
Kimberly L Weisgrau
Laura E Valentine
Nancy A Wilson
Saverio V Capuano
P2860
P304
P356
10.1128/JVI.02392-06
P407
P577
2007-01-24T00:00:00Z