A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system.
about
Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement componentsComplement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic ApproachesComplement and dysbiosis in periodontal diseasePeriodontitis: from microbial immune subversion to systemic inflammationStructure of the catalytic domain of theTannerella forsythiamatrix metallopeptidase karilysin in complex with a tetrapeptidic inhibitorA phage display selected 7-mer peptide inhibitor of the Tannerella forsythia metalloprotease-like enzyme Karilysin can be truncated to Ser-Trp-Phe-ProGenetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis.Staphylococcal proteases aid in evasion of the human complement system.A pathogenic trace of Tannerella forsythia - shedding of soluble fully active tumor necrosis factor α from the macrophage surface by karilysin.The inflammophilic character of the periodontitis-associated microbiotaRole of complement in host-microbe homeostasis of the periodontium.Single cell genomics of uncultured, health-associated Tannerella BU063 (Oral Taxon 286) and comparison to the closely related pathogen Tannerella forsythia.Polymicrobial synergy and dysbiosis in inflammatory disease.KLIKK proteases of Tannerella forsythia: putative virulence factors with a unique domain structurePeriodontopathogen levels following the use of an Er:YAG laser in the treatment of chronic periodontitis.A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement SystemProtease-dependent mechanisms of complement evasion by bacterial pathogens.Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia.Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention.The surface layer of Tannerella forsythia contributes to serum resistance and oral bacterial coaggregation.Human neutrophils and oral microbiota: a constant tug-of-war between a harmonious and a discordant coexistence.The complement system and its role in the pathogenesis of periodontitis: current concepts.Gingipain-dependent augmentation by Porphyromonas gingivalis of phagocytosis of Tannerella forsythia.Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes anaphylatoxin C5a activity.Gingipain-dependent degradation of mammalian target of rapamycin pathway proteins by the periodontal pathogen Porphyromonas gingivalis during invasion.Evasion Mechanisms Used by Pathogens to Escape the Lectin Complement PathwayNecroptosis in the periodontal homeostasis: Signals emanating from dying cells.BGA66 and BGA71 facilitate complement resistance of Borrelia bavariensis by inhibiting assembly of the membrane attack complex.FACIN, a Double-Edged Sword of the Emerging Periodontal Pathogen Filifactor alocis: A Metabolic Enzyme Moonlighting as a Complement Inhibitor.Tannerella forsythia GroEL induces inflammatory bone resorption and synergizes with interleukin-17.Ecological Therapeutic Opportunities for Oral Diseases.A novel mechanism of latency in matrix metalloproteinases.IgG sera levels against a subset of periodontopathogens and severity of disease in aggressive periodontitis patients: a cross-sectional study of selected pocket sites.Microbiota at teeth and implants in partially edentulous patients. A 10-year retrospective study.Revisiting the Page & Schroeder model: the good, the bad and the unknowns in the periodontal host response 40 years later.In vivo expression of proteases and protease inhibitor, a serpin, by periodontal pathogens at teeth and implants.
P2860
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P2860
A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A metalloproteinase karilysin ...... ways of the complement system.
@ast
A metalloproteinase karilysin ...... ways of the complement system.
@en
type
label
A metalloproteinase karilysin ...... ways of the complement system.
@ast
A metalloproteinase karilysin ...... ways of the complement system.
@en
prefLabel
A metalloproteinase karilysin ...... ways of the complement system.
@ast
A metalloproteinase karilysin ...... ways of the complement system.
@en
P2093
P2860
P50
P356
P1476
A metalloproteinase karilysin ...... ways of the complement system.
@en
P2093
Miroslaw Ksiazek
Monika Jusko
Sigrun Eick
P2860
P304
P356
10.4049/JIMMUNOL.1101240
P407
P577
2012-01-27T00:00:00Z