Increased expression of adenylylcyclase type VI proportionately increases beta-adrenergic receptor-stimulated production of cAMP in neonatal rat cardiac myocytes
about
Characterisation of human adenylyl cyclase IX reveals inhibition by Ca(2+)/Calcineurin and differential mRNA plyadenylationDevelopmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling.Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling.Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposureDevelopmental neurotoxicity elicited by gestational exposure to chlorpyrifos: when is adenylyl cyclase a target?Prospects for gene transfer for clinical heart failureCompartmentalization of β-adrenergic signals in cardiomyocytesAngiotensin II enhances adenylyl cyclase signaling via Ca2+/calmodulin. Gq-Gs cross-talk regulates collagen production in cardiac fibroblastsNitric oxide inhibition of adenylyl cyclase type 6 activity is dependent upon lipid rafts and caveolin signaling complexesExpression, characterization, and purification of C-terminally hexahistidine-tagged thromboxane A2 receptors.Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells.Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylyl cyclase.Coordinate down-regulation of adenylyl cyclase isoforms and the stimulatory G protein (G(s)) in intestinal epithelial cell differentiation.Variable imprinting of the heterotrimeric G protein G(s) alpha-subunit within different segments of the nephron.Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.Equilibrium between adenylyl cyclase and phosphodiesterase patterns adrenergic agonist dose-dependent spatiotemporal cAMP/protein kinase A activities in cardiomyocytes.Targeted transgenesis identifies Gαs as the bottleneck in β2-adrenergic receptor cell signaling and physiological function in airway smooth muscle.Paradoxical attenuation of β2-AR function in airway smooth muscle by Gi-mediated counterregulation in transgenic mice overexpressing type 5 adenylyl cyclase.Effect of overexpressed adenylyl cyclase VI on beta 1- and beta 2-adrenoceptor responses in adult rat ventricular myocytesEmerging therapeutic targets in chronic heart failure: part II.A kinase-anchoring proteins and adenylyl cyclase in cardiovascular physiology and pathology.Compartmentation of cAMP signaling in cardiac myocytes: a computational study.Thyroid hormone and adrenergic signaling in the heart.Adenylyl cyclase 2 selectively couples to E prostanoid type 2 receptors, whereas adenylyl cyclase 3 is not receptor-regulated in airway smooth muscle.New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy.Adenylyl cyclase gene transfer in heart failure.Adenylyl cyclase type 6 overexpression selectively enhances beta-adrenergic and prostacyclin receptor-mediated inhibition of cardiac fibroblast function because of colocalization in lipid rafts.Bitransgenesis with beta(2)-adrenergic receptors or adenylyl cyclase fails to improve beta(1)-adrenergic receptor cardiomyopathy.Unanticipated signaling events associated with cardiac adenylyl cyclase gene transfer.Adenylyl cyclase type VI gene transfer reduces phospholamban expression in cardiac myocytes via activating transcription factor 3.Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure: A Randomized Clinical TrialInternational Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction.Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity.Modulation of glucagon receptor expression and response in transfected human embryonic kidney cells.The olfactory G protein G(alphaolf) possesses a lower GDP-affinity and deactivates more rapidly than G(salphashort): consequences for receptor-coupling and adenylyl cyclase activation.Differential regulation of vascular tone and remodeling via stimulation of type 2 and type 6 adenylyl cyclases in the ductus arteriosus.Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes.beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling.Galphaq reduces cAMP production by decreasing Galphas protein abundance.
P2860
Q24290249-9654A364-A35E-41BD-A844-EB9D0BE2376CQ24810873-6D4045AC-07E8-4F4E-89C6-59E00571C0C6Q24810907-1BB9928D-5B23-4940-B716-E28D78059230Q24811167-E4B69B52-8EE9-4550-A614-9C13138C4980Q24816964-8A7E8A58-E4E1-45A9-9B98-54BD804F12B0Q26830145-937B8E71-8EFD-415D-A71F-073A3EE58308Q27026992-1A3AD384-B961-4D3A-AB6F-CBBFA592E6DEQ28569021-DD8EF9AC-0ED6-4302-8474-FF7D91497627Q28573679-628C5622-55BA-4BA3-87CB-46B6838DA162Q32035935-87B01004-5D44-4B96-9558-C02D94C910A5Q33618981-3827C376-EF35-4406-8A6A-01B17C242329Q33723868-D5BE7AD8-CB59-47BE-BD5C-DAEB6FD0CA76Q33800004-678AA4FD-368E-47C4-BC17-D4505147D5E7Q33883551-BAD1CA70-02F8-4078-A3D0-B25C8E1347F6Q33916995-0B8AFFD2-2E84-410A-A1FA-D0F8D9ACC25BQ34127946-B616EF5E-B85B-4CF3-AE06-6A8EC27882D5Q34519352-769558AF-D40F-4F17-8F44-292035320F43Q34720210-F7257A70-86E2-40C5-B4DD-644C31AF0251Q35047766-24A64CBD-8DC4-49C5-B18A-F23EA77C90D6Q35056026-638FD5CE-D7A7-4435-96EB-E494D2CFA06AQ35328208-EA3B2B0A-793B-4810-A7F3-B9FEDA4314F1Q35751497-D57A6C12-AC5C-45D2-B46C-B8FA5E849744Q35990314-7D011532-93E7-4998-9A4A-751BC79EA2FEQ36105393-DC3F20E7-9744-4FC3-97CF-4B61AD743AB5Q36515530-CDBAB822-5CEE-48F7-9E48-A8C3A6BE6C18Q36667369-7501858D-EF91-4FD9-B78D-17C953E33BF3Q37150683-394AB094-F045-4CF1-8B18-CCBC4B163EFEQ37700355-2EA6873C-F1ED-4DD3-AF97-22107D9120BDQ37847462-B83EE3F6-8D9F-4B00-841B-CF50C8230722Q38339372-627E9D4D-8302-477A-B76C-59293F37758BQ38389875-1D2C30E1-0DCE-4860-BD9B-64A991F9DD26Q39158851-5759330E-827E-4E15-A3A1-6A28C950758BQ39970283-0363C9EC-4D41-4682-9ABE-BD144A1525DDQ40770003-1F9B877F-7A74-46AE-9197-FB18B3E50B5BQ40781759-EF0BBBF0-9D2A-4FF2-BF84-5DD5F93DD214Q40791394-472565FD-0484-4E23-9E49-E34A0C04BF9EQ41473894-1FC66687-4B5F-4A90-80BC-197C98F615D7Q41679252-A617EAE3-B9CE-4529-8D2B-449AE9774A24Q42068044-BEE9A324-0BCC-4ACA-9FE1-E0137AA58242Q42443665-609F19B7-1358-4849-A536-73989CC612C0
P2860
Increased expression of adenylylcyclase type VI proportionately increases beta-adrenergic receptor-stimulated production of cAMP in neonatal rat cardiac myocytes
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Increased expression of adenyl ...... neonatal rat cardiac myocytes
@ast
Increased expression of adenyl ...... neonatal rat cardiac myocytes
@en
type
label
Increased expression of adenyl ...... neonatal rat cardiac myocytes
@ast
Increased expression of adenyl ...... neonatal rat cardiac myocytes
@en
prefLabel
Increased expression of adenyl ...... neonatal rat cardiac myocytes
@ast
Increased expression of adenyl ...... neonatal rat cardiac myocytes
@en
P2093
P2860
P356
P1476
Increased expression of adenyl ...... neonatal rat cardiac myocytes
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.3.1038
P407
P50
P577
1998-02-01T00:00:00Z