Hormone therapy: physiological complexity belies therapeutic simplicity.
about
Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptorsGrowth factor regulation of estrogen receptor coregulator PELP1 functions via Protein Kinase A pathwayEstrogen, aging and the cardiovascular systemAging, estrogen loss and epoxyeicosatrienoic acids (EETs)Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1Embodiment: a conceptual glossary for epidemiology.Genistein improves 3-NPA-induced memory impairment in ovariectomized rats: impact of its antioxidant, anti-inflammatory and acetylcholinesterase modulatory properties.Pharmaco- and toxicokinetics of selected exogenous and endogenous estrogens: a review of the data and identification of knowledge gaps.Bone mass is preserved and cancellous architecture altered due to cyclic loading of the mouse tibia after orchidectomy.Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation.DNA binding by estrogen receptor-alpha is essential for the transcriptional response to estrogen in the liver and the uterusIncreased risk of dementia in patients with osteoporosis: a population-based retrospective cohort analysis.Estradiol is a potent protective, restorative, and trophic factor after brain injury.An innovative method to classify SERMs based on the dynamics of estrogen receptor transcriptional activity in living animals.Uterotrophic effects of cow milk in immature ovariectomized Sprague-Dawley ratsEstradiol regulates susceptibility following primary exposure to genital herpes simplex virus type 2, while progesterone induces inflammation.Reciprocal regulation of adipocyte and osteoblast differentiation of mesenchymal stem cells by Eupatorium japonicum prevents bone loss and adiposity increase in osteoporotic rats.Hormone therapy for the ageing. Despite the negative results of recent trials, hormone replacement therapy retains enticing promises for the elderly.Optimal management of perimenopausal depressionEstrogen effects on vascular inflammation are age dependent: role of estrogen receptors.Parenteral oestrogen in the treatment of prostate cancer: a systematic reviewG protein-coupled estrogen receptor protects from atherosclerosis27-Hydroxycholesterol: the first identified endogenous SERMEstrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases.Estrogen signaling in the cardiovascular system.The conundrum of estrogen receptor oscillatory activity in the search for an appropriate hormone replacement therapy.Gender differences in cardiovascular disease: hormonal and biochemical influences.Liganded and unliganded activation of estrogen receptor and hormone replacement therapies.Differential Neuroprotection of Selective Estrogen Receptor Agonists against Autonomic Dysfunction and Ischemic Cell Death in Permanent versus Reperfusion Injury.A critique of Women's Health Initiative Studies (2002-2006)Impact of aging vs. estrogen loss on cardiac gene expression: estrogen replacement and inflammationEstrogen and P2 Purinergic Receptor Systems in Microglia: Therapeutic Targets for Neuroprotection.Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65.Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions.Aging, Angiotensin system and dopaminergic degeneration in the substantia nigra.Structure-nongenomic neuroprotection relationship of estrogens and estrogen-derived compounds.17beta-Estradiol reverses shear-stress-mediated low density lipoprotein modifications.Treatment of menopausal symptoms post-Women's Health Initiative: refinement of existing treatments and development of new therapies.Preliminary evidence that long-term estrogen use reduces white matter loss in aging.Age alters cerebrovascular inflammation and effects of estrogen.
P2860
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P2860
Hormone therapy: physiological complexity belies therapeutic simplicity.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hormone therapy: physiological complexity belies therapeutic simplicity.
@ast
Hormone therapy: physiological complexity belies therapeutic simplicity.
@en
type
label
Hormone therapy: physiological complexity belies therapeutic simplicity.
@ast
Hormone therapy: physiological complexity belies therapeutic simplicity.
@en
prefLabel
Hormone therapy: physiological complexity belies therapeutic simplicity.
@ast
Hormone therapy: physiological complexity belies therapeutic simplicity.
@en
P2093
P356
P1433
P1476
Hormone therapy: physiological complexity belies therapeutic simplicity.
@en
P2093
Donald P McDonnell
Judith L Turgeon
Kathryn A Martin
Phyllis M Wise
P304
P356
10.1126/SCIENCE.1096725
P407
P577
2004-05-01T00:00:00Z