Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice
about
Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrinMegakaryocytes, malignancy and bone marrow vascular nichesCD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1The circadian clock in cancer development and therapyThrombospondin 1 and vasoactive agents indirectly alter tumor blood flow.Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts.E2F-1 directly regulates thrombospondin 1 expression.Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressorsPlatelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis.Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1.Aberrations in Angiogenic Signaling and MYC Amplifications are Distinguishing Features of Angiosarcoma.DNA methylation profile distinguishes clear cell sarcoma of the kidney from other pediatric renal tumorsThe thrombospondins.Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis.Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).Biomarkers and the genetics of early neoplastic lesions.Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.CD47: a new target in cardiovascular therapy.Thrombospondin-1: a physiological regulator of nitric oxide signalingThe role of thrombospondin 1 on intestinal inflammation and carcinogenesisThe biologic significance of micrometastatic disease and sentinel lymph node technology on colorectal cancer.Thrombospondins in cancer.The effect of thrombospondin-1 on breast cancer metastasisDietary fat overcomes the protective activity of thrombospondin-1 signaling in the Apc(Min/+) model of colon cancer.Estrogen regulation of thrombospondin-1 in human breast cancer cells.Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapiesAngiogenesis, vasculogenic mimicry and vascular invasion in cutaneous malignant melanoma - implications for therapeutic strategies and targeted therapies.Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment.Functions and transcriptional regulation of thrombospondins and their interrelationship with fibroblast growth factor-2 in bovine luteal cells.Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level.Elongation factor ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation.Systemic administration of attenuated Salmonella choleraesuis carrying thrombospondin-1 gene leads to tumor-specific transgene expression, delayed tumor growth and prolonged survival in the murine melanoma model.Thrombospondin-1 promotes cell migration, invasion and lung metastasis of osteosarcoma through FAK dependent pathway.Integration of pro- and anti-angiogenic signals by endothelial cells.Lack of thrombospondin-1 increases angiogenesis in a model of chronic inflammatory bowel disease.
P2860
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P2860
Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Thrombospondin-1 gene expressi ...... spectrum of p53-deficient mice
@ast
Thrombospondin-1 gene expressi ...... spectrum of p53-deficient mice
@en
type
label
Thrombospondin-1 gene expressi ...... spectrum of p53-deficient mice
@ast
Thrombospondin-1 gene expressi ...... spectrum of p53-deficient mice
@en
prefLabel
Thrombospondin-1 gene expressi ...... spectrum of p53-deficient mice
@ast
Thrombospondin-1 gene expressi ...... spectrum of p53-deficient mice
@en
P2093
P2860
P1476
Thrombospondin-1 gene expressi ...... spectrum of p53-deficient mice
@en
P2093
P2860
P304
P356
10.1016/S0002-9440(10)63042-8
P407
P577
2001-11-01T00:00:00Z