Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo.
about
Receptor and secreted targets of Wnt-1/beta-catenin signalling in mouse mammary epithelial cellsAssociation of matrix metalloproteinase 2 plasma level with response and survival in patients treated with bevacizumab for recurrent high-grade glioma.Adrenomedullin in ovarian cancer: foe in vitro and friend in vivo?Ubiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenaseTumor-expressed adrenomedullin accelerates breast cancer bone metastasis.Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.Angiogenesis in gliomas: imaging and experimental therapeutics.Adrenomedullin, an autocrine/paracrine factor induced by androgen withdrawal, stimulates 'neuroendocrine phenotype' in LNCaP prostate tumor cells.Expression and role of adrenomedullin in renal tumors and value of its mRNA levels as prognostic factor in clear-cell renal carcinoma.HIFs enhance the transcriptional activation and splicing of adrenomedullin.Adrenomedullin as a therapeutic target in angiogenesis.Interleukin-1β promotes hypoxia-induced apoptosis of glioblastoma cells by inhibiting hypoxia-inducible factor-1 mediated adrenomedullin productionGrowth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivoTranscriptional regulation of adrenomedullin by oncostatin M in human astroglioma cells: implications for tumor invasion and migrationBioinformatics-based discovery and identification of new biologically active peptides for GPCR deorphanization.An angiogenic role for adrenomedullin in choroidal neovascularization.Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice.Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis.Adrenomedullin Function in Vascular Endothelial Cells: Insights from Genetic Mouse Models.Correlation of adrenomedullin with the erythropoietin receptor and microvessel density in hepatocellular carcinomaEndo/exo-proteolysis in neoplastic progression and metastasis.Adrenomedullin and tumour angiogenesis.Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer.Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo.Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition.Peptide processing and biology in human disease.Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers.Adrenomedullin promotes angiogenesis in epithelial ovarian cancer through upregulating hypoxia-inducible factor-1α and vascular endothelial growth factor.Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretionAdrenomedullin and tumour microenvironment.Adrenomedullin expression does not correlate with survival in lung cancer.Elevated expression of adrenomedullin is correlated with prognosis and disease severity in osteosarcoma.The expression of calcitonin receptor detected in malignant cells of the brain tumour glioblastoma multiforme and functional properties in the cell line A172.A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease.Adrenomedullin is induced by hypoxia and enhances pancreatic cancer cell invasion.PTEN inhibits adrenomedullin expression and function in brain tumor cells.Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin.Gene expression profiling identifies IL-13 receptor alpha 2 chain as a therapeutic target in prostate tumor cells overexpressing adrenomedullin.Adrenomedullin blockade induces regression of tumor neovessels through interference with vascular endothelial-cadherin signalling.Lack of adrenomedullin in mouse endothelial cells results in defective angiogenesis, enhanced vascular permeability, less metastasis, and more brain damage.
P2860
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P2860
Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Neutralization of adrenomedull ...... umor xenograft growth in vivo.
@ast
Neutralization of adrenomedull ...... umor xenograft growth in vivo.
@en
type
label
Neutralization of adrenomedull ...... umor xenograft growth in vivo.
@ast
Neutralization of adrenomedull ...... umor xenograft growth in vivo.
@en
prefLabel
Neutralization of adrenomedull ...... umor xenograft growth in vivo.
@ast
Neutralization of adrenomedull ...... umor xenograft growth in vivo.
@en
P2093
P2860
P1476
Neutralization of adrenomedull ...... umor xenograft growth in vivo.
@en
P2093
Christine Delfino
Christophe Dussert
François Grisoli
Frédéric Fina
Henri Dufour
Jacqueline Palmari
Nils Brünner
Olivier Chinot
Pierre Casellas
Pierre-Marie Martin
P2860
P304
P356
10.1016/S0002-9440(10)62555-2
P407
P577
2002-04-01T00:00:00Z