Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma - Wikidata - awgldk - TriplyDB

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma

http://www.wikidata.org/entity/Q35800124

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Additive effects of cherlerythrine chloride combination with erlotinib in human non-small cell lung cancer cells.Loss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein kinase C (aPKC)/NF-κB/interleukin-6 (IL-6) axis in mouse mammary cells.Urotensin-II receptor stimulation of cardiac L-type Ca2+ channels requires the βγ subunits of Gi/o-protein and phosphatidylinositol 3-kinase-dependent protein kinase C β1 isoform.Expression of polarity genes in human cancer.Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma.Zeta Inhibitory Peptide Disrupts Electrostatic Interactions That Maintain Atypical Protein Kinase C in Its Active Conformation on the Scaffold p62.Phosphorylation of NR2B NMDA subunits by protein kinase C in arcuate nucleus contributes to inflammatory pain in rats Histone Deacetylase-3/CAGE Axis Targets EGFR Signaling and Regulates the Response to Anti-Cancer Drugs Protein Scaffolds Control Localized Protein Kinase Cζ Activity.Hypertonic saline protects brain endothelial cells against hypoxia correlated to the levels of epidermal growth factor receptor and interleukin-1β.Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor.Protein kinase C as a tumor suppressor.Melatonin-mediated inhibition of Purkinje neuron P-type Ca²⁺ channels in vitro induces neuronal hyperexcitability through the phosphatidylinositol 3-kinase-dependent protein kinase C delta pathway.Tumor-derived fibulin-3 activates pro-invasive NF-κB signaling in glioblastoma cells and their microenvironment.Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism.Failure of the PTEN/aPKC/Lgl Axis Primes Formation of Adult Brain Tumours in Drosophila.Regulatory effects of miR-155 and miR-146a on repolarization and inflammatory cytokine secretion in human alveolar macrophages in vitro.aPKCζ-dependent Repression of Yap is Necessary for Functional Restoration of Irradiated Salivary Glands with IGF-1.ω-3 and ω-6 Fatty Acids Modulate Conventional and Atypical Protein Kinase C Activities in a Brain Fatty Acid Binding Protein Dependent Manner in Glioblastoma Multiforme.Protein kinase C: perfectly balanced.Macrophages and Galectin 3 Control Bacterial Burden in Acute and Subacute Murine Leptospirosis That Determines Chronic Kidney Fibrosis

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Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma

http://www.wikidata.org/entity/Q35800124

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

Targeting aPKC disables oncoge ...... cytokine TNFα in glioblastoma

@ast

Targeting aPKC disables oncoge ...... cytokine TNFα in glioblastoma

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type

label

Targeting aPKC disables oncoge ...... cytokine TNFα in glioblastoma

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Targeting aPKC disables oncoge ...... cytokine TNFα in glioblastoma

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prefLabel

Targeting aPKC disables oncoge ...... cytokine TNFα in glioblastoma

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Targeting aPKC disables oncoge ...... cytokine TNFα in glioblastoma

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SCISIGNAL.2005196

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Science Signaling

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Targeting aPKC disables oncoge ...... cytokine TNFα in glioblastoma

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P2093

Andrea E Errasti

http://www.w3.org/2001/XMLSchema#string

Anthony S Perry

http://www.w3.org/2001/XMLSchema#string

Christopher Hulme

http://www.w3.org/2001/XMLSchema#string

Daniel Gibbs

http://www.w3.org/2001/XMLSchema#string

Edward K Mandell

http://www.w3.org/2001/XMLSchema#string

Elisabeth J Rushing

http://www.w3.org/2001/XMLSchema#string

Eugenio A Carrera-Silva

http://www.w3.org/2001/XMLSchema#string

Joseph C Loftus

http://www.w3.org/2001/XMLSchema#string

Justin D Dietrich

http://www.w3.org/2001/XMLSchema#string

Kenneth Aldape

http://www.w3.org/2001/XMLSchema#string

P2860

EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma

Inflammation and cancer

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a src kinase pathway.

Neutralizing tumor-promoting chronic inflammation: a magic bullet?

Will kinase inhibitors make it as glioblastoma drugs?

2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

Cancer-related inflammation

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

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10.1126/SCISIGNAL.2005196

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Carla V. Rothlin

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2014-08-12T00:00:00Z

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265208501

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