Intranuclear targeting and nuclear export of the adenovirus E1B-55K protein are regulated by SUMO1 conjugation.
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SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PMLOncolytic Replication of E1b-Deleted AdenovirusesViral Mimicry to Usurp Ubiquitin and SUMO Host PathwaysAdenovirus Early Proteins and Host SumoylationAdenovirus type 5 early region 1B 55-kDa oncoprotein can promote cell transformation by a mechanism independent from blocking p53-activated transcriptionAdenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cellsSPOC1-mediated antiviral host cell response is antagonized early in human adenovirus type 5 infectionLocalization and importance of the adenovirus E4orf4 protein during lytic infectionAdenovirus E1B 55-kilodalton protein is a p53-SUMO1 E3 ligase that represses p53 and stimulates its nuclear export through interactions with promyelocytic leukemia nuclear bodies.Interaction of adenovirus type 5 E4orf4 with the nuclear pore subunit Nup205 is required for proper viral gene expression.A ubiquitin-specific protease possesses a decisive role for adenovirus replication and oncogene-mediated transformation.Sumoylation inhibits alpha-synuclein aggregation and toxicity.Role of the RNA recognition motif of the E1B 55 kDa protein in the adenovirus type 5 infectious cycle.KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO ModificationControl of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activityIdentification of a nuclear export signal sequence for bovine papillomavirus E1 protein.Aggresome formation by the adenoviral protein E1B55K is not conserved among adenovirus species and is not required for efficient degradation of nuclear substratesRegulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers.Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryoAdenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation.The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function.Nucleocytoplasmic functions of the PDZ-LIM protein family: new insights into organ development.Human pathogens and the host cell SUMOylation system.Sp100 isoform-specific regulation of human adenovirus 5 gene expression.Role of E1B55K in E4orf6/E1B55K E3 ligase complexes formed by different human adenovirus serotypes.Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.Functional cooperation between human adenovirus type 5 early region 4, open reading frame 6 protein, and cellular homeobox protein HoxB7.The human adenovirus type 5 E1B 55-kilodalton protein is phosphorylated by protein kinase CK2.CRM1-dependent transport supports cytoplasmic accumulation of adenoviral early transcripts.Proteasome-dependent degradation of Daxx by the viral E1B-55K protein in human adenovirus-infected cells.Arginine methylation of human adenovirus type 5 L4 100-kilodalton protein is required for efficient virus production.SUMOylation regulates nuclear localization of Krüppel-like factor 5.Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates.Viral Interplay with the Host Sumoylation System.Humanized Mice Reproduce Acute and Persistent Human Adenovirus Infection.The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Enhances E1A Functional Activity.The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Can Mimic E1A Effects on E2F.PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53.The E3 ubiquitin ligase activity associated with the adenoviral E1B-55K-E4orf6 complex does not require CRM1-dependent export.A 49-kilodalton isoform of the adenovirus type 5 early region 1B 55-kilodalton protein is sufficient to support virus replication
P2860
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P2860
Intranuclear targeting and nuclear export of the adenovirus E1B-55K protein are regulated by SUMO1 conjugation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Intranuclear targeting and nuc ...... egulated by SUMO1 conjugation.
@ast
Intranuclear targeting and nuc ...... egulated by SUMO1 conjugation.
@en
type
label
Intranuclear targeting and nuc ...... egulated by SUMO1 conjugation.
@ast
Intranuclear targeting and nuc ...... egulated by SUMO1 conjugation.
@en
prefLabel
Intranuclear targeting and nuc ...... egulated by SUMO1 conjugation.
@ast
Intranuclear targeting and nuc ...... egulated by SUMO1 conjugation.
@en
P2093
P2860
P356
P1476
Intranuclear targeting and nuc ...... egulated by SUMO1 conjugation.
@en
P2093
Barbara Härtl
Joachim Hauber
Kathrin Kindsmüller
Paola Blanchette
Peter Groitl
Thomas Dobner
P2860
P304
P356
10.1073/PNAS.0702158104
P407
P577
2007-04-11T00:00:00Z