Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation.
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Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate SpecificityThe PRMT5 arginine methyltransferase: many roles in development, cancer and beyondReciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizuresPRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.).Prmt5 is a regulator of muscle stem cell expansion in adult mice.Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene ExpressionTranscriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells.AP1 transcription factors in epidermal differentiation and skin cancerMEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.
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P2860
Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Protein arginine methyltransfe ...... keratinocyte differentiation.
@ast
Protein arginine methyltransfe ...... keratinocyte differentiation.
@en
type
label
Protein arginine methyltransfe ...... keratinocyte differentiation.
@ast
Protein arginine methyltransfe ...... keratinocyte differentiation.
@en
prefLabel
Protein arginine methyltransfe ...... keratinocyte differentiation.
@ast
Protein arginine methyltransfe ...... keratinocyte differentiation.
@en
P2860
P356
P1476
Protein arginine methyltransfe ...... keratinocyte differentiation.
@en
P2093
Richard L Eckert
Santosh R Kanade
P2860
P304
P356
10.1074/JBC.M111.331660
P407
P577
2011-12-23T00:00:00Z