Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunit

Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunit

Item
http://www.wikidata.org/entity/Q35802730
Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxinDeterminants of the specificity of rotavirus interactions with the alpha2beta1 integrinRotavirus activates JNK and p38 signaling pathways in intestinal cells, leading to AP-1-driven transcriptional responses and enhanced virus replicationRotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset.Rotavirus replication in intestinal cells differentially regulates integrin expression by a phosphatidylinositol 3-kinase-dependent pathway, resulting in increased cell adhesion and virus yield.Integrin-using rotaviruses bind alpha2beta1 integrin alpha2 I domain via VP4 DGE sequence and recognize alphaXbeta2 and alphaVbeta3 by using VP7 during cell entryCholangiocyte expression of alpha2beta1-integrin confers susceptibility to rotavirus-induced experimental biliary atresia.VP7 mediates the interaction of rotaviruses with integrin alphavbeta3 through a novel integrin-binding site.Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences.Relative roles of GM1 ganglioside, N-acylneuraminic acids, and α2β1 integrin in mediating rotavirus infection.Carbohydrate recognition by rotaviruses.A Point Mutation in the Rhesus Rotavirus VP4 Protein Generated through a Rotavirus Reverse Genetics System Attenuates Biliary Atresia in the Murine Model.The SRL peptide of rhesus rotavirus VP4 protein governs cholangiocyte infection and the murine model of biliary atresia.
P2860

Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunit

Item
http://www.wikidata.org/entity/Q35802730
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Monkey rotavirus binding to al ...... y the homologous beta1 subunit
@ast
Monkey rotavirus binding to al ...... y the homologous beta1 subunit
@en
type
label
Monkey rotavirus binding to al ...... y the homologous beta1 subunit
@ast
Monkey rotavirus binding to al ...... y the homologous beta1 subunit
@en
prefLabel
Monkey rotavirus binding to al ...... y the homologous beta1 subunit
@ast
Monkey rotavirus binding to al ...... y the homologous beta1 subunit
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Monkey rotavirus binding to al ...... y the homologous beta1 subunit
@en
P2093
P2860
P304
P31
P356
10.1128/JVI.77.17.9486-9501.2003
P407
P433
P478
P50
P577
P5875
P698
P932