Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans. - Wikidata - awgldk - TriplyDB

Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans.

Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans.

http://www.wikidata.org/entity/Q35812810

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Lipidomics-Reshaping the Analysis and Perception of Type 2 Diabetes Positive effects of voluntary running on metabolic syndrome-related disorders in non-obese hereditary hypertriacylglycerolemic rats MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice.Training status diverges muscle diacylglycerol accumulation during free fatty acid elevation Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects.Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism.The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes Serum sphingolipids: relationships to insulin sensitivity and changes with exercise in humans.Obesity and endoplasmic reticulum (ER) stresses.Exercise and Weight Loss Improve Muscle Mitochondrial Respiration, Lipid Partitioning, and Insulin Sensitivity After Gastric Bypass Surgery.IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity.Mechanism by Which Caloric Restriction Improves Insulin Sensitivity in Sedentary Obese Adults.Novel and reversible mechanisms of smoking-induced insulin resistance in humans.Biomarkers of Ectopic Fat Deposition: The Next Frontier in Serum Lipidomics.CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance.Skeletal intramyocellular lipid metabolism and insulin resistance.Altered Skeletal Muscle Fatty Acid Handling in Subjects with Impaired Glucose Tolerance as Compared to Impaired Fasting Glucose.Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db/db mice.Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans.Relative Contribution of Intramyocellular Lipid to Whole-Body Fat Oxidation Is Reduced With Age but Subsarcolemmal Lipid Accumulation and Insulin Resistance Are Only Associated With Overweight Individuals.Role of intramyocelluar lipids in human health Mechanisms underlying the onset of oral lipid-induced skeletal muscle insulin resistance in humans Insulin-mediated suppression of lipolysis in adipose tissue and skeletal muscle of obese type 2 diabetic men and men with normal glucose tolerance Training Does Not Alter Muscle Ceramide and Diacylglycerol in Offsprings of Type 2 Diabetic Patients Despite Improved Insulin Sensitivity.Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance.A sustained increase in plasma NEFA upregulates the Toll-like receptor network in human muscle.Revisiting the diacylglycerol-induced insulin resistance hypothesis.Metabolic syndrome in youth: current insights and novel serum biomarkers.Fatty acids and cardiac disease: fuel carrying a message.Intracellular lipid accumulation and shift during diabetes progression.Role of endoplasmic reticulum stress in atherosclerosis and diabetic macrovascular complications.Lipid-mediated muscle insulin resistance: different fat, different pathways?Targeting fatty acid metabolism to improve glucose metabolism.Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice.Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle.

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Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans.

http://www.wikidata.org/entity/Q35812810

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2012 nî lūn-bûn

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2012年の論文

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2012年论文

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2012年论文

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Localisation and composition o ...... insulin resistance in humans.

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Localisation and composition o ...... insulin resistance in humans.

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Localisation and composition o ...... s insulin resistance in humans

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A Kerege

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B C Bergman

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D M Hunerdosse

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L Perreault

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P2860

Diacylglycerol kinase delta suppresses ER-to-Golgi traffic via its SAM and PH domains

Diacylglycerol kinase-zeta localization in skeletal muscle is regulated by phosphorylation and interaction with syntrophins

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex.

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

Activation of protein kinase C by coexisting diacylglycerol-enriched and diacylglycerol-poor lipid domains.

DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells.

Insulin resistance is associated with higher intramyocellular triglycerides in type I but not type II myocytes concomitant with higher ceramide content.

Increased intramuscular lipid synthesis and low saturation relate to insulin sensitivity in endurance-trained athletes.

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