Investigation of the mechanism of clearance of AMG 386, a selective angiopoietin-1/2 neutralizing peptibody, in splenectomized, nephrectomized, and FcRn knockout rodent models.
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Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and developmentPharmacokinetic drug-drug interaction assessment of peptibody trebananib in combination with chemotherapies.A Pharmacokinetic and Safety Study of Trebananib, an Fc-Fusion Peptibody, in Patients With Advanced Solid Tumors and Varying Degrees of Renal Dysfunction.Pharmacokinetic drug-drug interaction study of the angiopoietin-1/angiopoietin-2-inhibiting peptibody trebananib (AMG 386) and paclitaxel in patients with advanced solid tumors.Pediatric Phase I Trial and Pharmacokinetic Study of Trebananib in Relapsed Solid Tumors, Including Primary Tumors of the Central Nervous System ADVL1115: A Children's Oncology Group Phase I Consortium Report.Peptibodies: An elegant solution for a long-standing problem.
P2860
Investigation of the mechanism of clearance of AMG 386, a selective angiopoietin-1/2 neutralizing peptibody, in splenectomized, nephrectomized, and FcRn knockout rodent models.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Investigation of the mechanism ...... d FcRn knockout rodent models.
@ast
Investigation of the mechanism ...... d FcRn knockout rodent models.
@en
type
label
Investigation of the mechanism ...... d FcRn knockout rodent models.
@ast
Investigation of the mechanism ...... d FcRn knockout rodent models.
@en
prefLabel
Investigation of the mechanism ...... d FcRn knockout rodent models.
@ast
Investigation of the mechanism ...... d FcRn knockout rodent models.
@en
P2093
P2860
P1476
Investigation of the mechanism ...... d FcRn knockout rodent models.
@en
P2093
Benjamin Wu
Dominador Calamba
Jessica Johnson
Manuel Ponce
Marcus Soto
Yu-Nien Sun
P2860
P304
P356
10.1007/S11095-011-0650-Z
P577
2011-12-22T00:00:00Z