Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload.
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Cardiac cAMP: production, hydrolysis, modulation and detectionMitochondria and cardiovascular agingSimilarly potent inhibition of adenylyl cyclase by P-site inhibitors in hearts from wild type and AC5 knockout miceMolecular targets in heart failure gene therapy: current controversies and translational perspectivesType 5 adenylyl cyclase disruption leads to enhanced exercise performanceAn adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytesAutosomal dominant familial dyskinesia and facial myokymia: single exome sequencing identifies a mutation in adenylyl cyclase 5.Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stressesMice lacking the Cβ subunit of PKA are resistant to angiotensin II-induced cardiac hypertrophy and dysfunction.Cardiac aging in mice and humans: the role of mitochondrial oxidative stressGene expression and β-adrenergic signaling are altered in hypoplastic left heart syndrome.Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload.Disruption of adenylyl cyclase type V does not rescue the phenotype of cardiac-specific overexpression of Galphaq protein-induced cardiomyopathyDisruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade.Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice.Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compoundsStimulation of renin secretion by catecholamines is dependent on adenylyl cyclases 5 and 6.Overexpression of adenylyl cyclase type 5 (AC5) confers a proarrhythmic substrate to the heartEffects of GRK5 and ADRB1 polymorphisms influence on systolic heart failureAKAPs: the architectural underpinnings of local cAMP signaling.Carbamazepine alone and in combination with doxycycline attenuates isoproterenol-induced cardiac hypertrophy.A kinase-anchoring proteins and adenylyl cyclase in cardiovascular physiology and pathology.Inhibition of adenylyl cyclase type 5 increases longevity and healthful aging through oxidative stress protectionProtective Effects of Clenbuterol against Dexamethasone-Induced Masseter Muscle Atrophy and Myosin Heavy Chain TransitionCardiac aging: from molecular mechanisms to significance in human health and diseaseCardiac Effects of Attenuating Gsα - Dependent SignalingPrevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclaseGenetic maneuvers to ameliorate ventricular function in heart failure: therapeutic potential and future implications.A conformational transition in the adenylyl cyclase catalytic site yields different binding modes for ribosyl-modified and unmodified nucleotide inhibitorsThe A-kinase anchoring protein Yotiao facilitates complex formation between adenylyl cyclase type 9 and the IKs potassium channel in heart.New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy.Type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flightCommon mechanisms for calorie restriction and adenylyl cyclase type 5 knockout models of longevityModulation of beta-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5.Gene therapy in heart failure.A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failureAdenylyl cyclase type 5 in cardiac disease, metabolism, and aging.Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies.Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy.Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury.
P2860
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P2860
Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Disruption of type 5 adenylyl ...... ion against pressure overload.
@ast
Disruption of type 5 adenylyl ...... ion against pressure overload.
@en
type
label
Disruption of type 5 adenylyl ...... ion against pressure overload.
@ast
Disruption of type 5 adenylyl ...... ion against pressure overload.
@en
prefLabel
Disruption of type 5 adenylyl ...... ion against pressure overload.
@ast
Disruption of type 5 adenylyl ...... ion against pressure overload.
@en
P2093
P2860
P356
P1476
Disruption of type 5 adenylyl ...... tion against pressure overload
@en
P2093
Chull Hong
Dorothy E Vatner
Gen Takagi
Guiping Yang
Jun-ichi Kawabe
Ming-Chih Lee
Satoshi Okumura
Stephen F Vatner
Yoshihiro Ishikawa
P2860
P304
P356
10.1073/PNAS.1733772100
P407
P577
2003-08-06T00:00:00Z