Unusual DNA structure of the diabetes susceptibility locus IDDM2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ.
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G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNADirect evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcriptionG4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysatesFormation and properties of hairpin and tetraplex structures of guanine-rich regulatory sequences of muscle-specific genesGuanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeatsGenetics of type 1 diabetes mellitusThe DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysatesIntramolecular DNA quadruplexes with different arrangements of short and long loopsCapture and identification of proteins that bind to a GGA-rich sequence from the ERBB2 gene promoter region.Insulin capture by an insulin-linked polymorphic region G-quadruplex DNA oligonucleotide.A genome-inspired DNA ligand for the affinity capture of insulin and insulin-like growth factor-2.Association of insulin-like growth factor 2 with the insulin-linked polymorphic region in cultured fetal thymus cells.An engineered zinc finger protein reveals a role for the insulin VNTR in the regulation of the insulin and adjacent IGF2 genes.Mass spectrometric determination of ILPR G-quadruplex binding sites in insulin and IGF-2.The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-elementG4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy.Making sense of G-quadruplex and i-motif functions in oncogene promoters.Secondary structure at a hot spot for DNA methylation in DNA from human breast cancers.Biological aspects of DNA/RNA quadruplexes.Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.The insulin gene in diabetes.Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.Induction of Ras by SAF-1/MAZ through a feed-forward loop promotes angiogenesis in breast cancer.Regulatory polymorphisms underlying complex disease traits.NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.G-quadruplex structures and their interaction diversity with ligands.NMR evaluation of ammonium ion movement within a unimolecular G-quadruplex in solution.Genome-wide analysis reveals regulatory role of G4 DNA in gene transcriptionMAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice.Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter.A hitchhiker's guide to G-quadruplex ligands.Direct experimental evidence for quadruplex-quadruplex interaction within the human ILPR.Genome-wide colonization of gene regulatory elements by G4 DNA motifsGenetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: role of the proximal promoter GC-rich region.A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity.A comparative study of the interactions of cationic hetarenes with quadruplex-DNA forming oligonucleotide sequences of the insulin-linked polymorphic region (ILPR).The relationship of potential G-quadruplex sequences in cis-upstream regions of the human genome to SP1-binding elements.Quadruplex structures of muscle gene promoter sequences enhance in vivo MyoD-dependent gene expression.Differential binding of quadruplex structures of muscle-specific genes regulatory sequences by MyoD, MRF4 and myogenin.
P2860
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P2860
Unusual DNA structure of the diabetes susceptibility locus IDDM2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Unusual DNA structure of the d ...... lin promoter factor Pur-1/MAZ.
@ast
Unusual DNA structure of the d ...... lin promoter factor Pur-1/MAZ.
@en
type
label
Unusual DNA structure of the d ...... lin promoter factor Pur-1/MAZ.
@ast
Unusual DNA structure of the d ...... lin promoter factor Pur-1/MAZ.
@en
prefLabel
Unusual DNA structure of the d ...... lin promoter factor Pur-1/MAZ.
@ast
Unusual DNA structure of the d ...... lin promoter factor Pur-1/MAZ.
@en
P2093
P2860
P356
P1476
Unusual DNA structure of the d ...... lin promoter factor Pur-1/MAZ.
@en
P2093
P2860
P304
12508-12512
P356
10.1073/PNAS.97.23.12508
P407
P577
2000-11-01T00:00:00Z