Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition
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Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell ProliferationCharacterization of the 26S proteasome network in Plasmodium falciparumThe anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.In vitro induction of erythrocyte phosphatidylserine translocation by the natural naphthoquinone shikonin.Tumor necrosis factor-α sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosisShikonin suppresses ERK 1/2 phosphorylation during the early stages of adipocyte differentiation in 3T3-L1 cells.The apoptotic effect of shikonin on human papillary thyroid carcinoma cells through mitochondrial pathway.The inhibitory effect of shikonin on the agonist-induced regulation of vascular contractility.Beneficial effect of shikonin on experimental colitis induced by dextran sulfate sodium in BALB/c miceApoptosis induced by β,β-dimethylacrylshikonin is associated with Bcl-2 and NF-κB in human breast carcinoma MCF-7 cells.PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species.Shikonin reduces endometriosis by inhibiting RANTES secretion and mononuclear macrophage chemotaxis.Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy.Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases.Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy.Shikonin and its derivatives: a patent review.Shikonin induces necroptosis by reactive oxygen species activation in nasopharyngeal carcinoma cell line CNE-2Z.Preparation, cellular uptake and angiogenic suppression of shikonin-containing liposomes in vitro and in vivo.Shikonin inhibits inflammation and chondrocyte apoptosis by regulation of the PI3K/Akt signaling pathway in a rat model of osteoarthritis.Shikonin Suppresses Human T Lymphocyte Activation through Inhibition of IKK β Activity and JNK PhosphorylationAntiviral activity of shikonin ester derivative PMM-034 against enterovirus 71 in vitro.Decreased adiposity and enhanced glucose tolerance in shikonin treated mice.Shikonin Promotes Skin Cell Proliferation and Inhibits Nuclear Factor-κB Translocation via Proteasome Inhibition In Vitro.Shikonin reduces tamoxifen resistance through long non-coding RNA uc.57.Shikonin protects against D-Galactosamine and lipopolysaccharide-induced acute hepatic injury by inhibiting TLR4 signaling pathway.Shikonin Inhibited Migration and Invasion of Human Lung Cancer Cells via Suppression of c-Met-Mediated Epithelial-to-Mesenchymal Transition.Development of a novel hollow-fiber liquid-phase microextraction based on oil-in-salt and its comparison with conventional one.Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance.Shikonin suppresses proliferation and induces apoptosis in endometrioid endometrial cancer cells via modulating miR-106b/PTEN/AKT/mTOR signaling pathway.Shikonin inhibits TNF-α production through suppressing PKC-NF-κB-dependent decrease of IL-10 in rheumatoid arthritis-like cell model.Shikonin inhibits TNF-α-induced growth and invasion of rat aortic vascular smooth muscle cells.Senescence Inducer Shikonin ROS-Dependently Suppressed Lung Cancer Progression.Shikonin Production by Callus Culture of Onosma bulbotrichom as Active Pharmaceutical Ingredient.Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer
P2860
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P2860
Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Shikonin extracted from medici ...... fect via proteasome inhibition
@ast
Shikonin extracted from medici ...... fect via proteasome inhibition
@en
type
label
Shikonin extracted from medici ...... fect via proteasome inhibition
@ast
Shikonin extracted from medici ...... fect via proteasome inhibition
@en
prefLabel
Shikonin extracted from medici ...... fect via proteasome inhibition
@ast
Shikonin extracted from medici ...... fect via proteasome inhibition
@en
P2093
P2860
P1476
Shikonin extracted from medici ...... fect via proteasome inhibition
@en
P2093
Aiping Qin
Change Zhang
Chuanyin Zhang
Guanmei Wen
Hongbiao Huang
Jinbao Liu
Ningning Liu
Q Ping Dou
P2860
P304
P356
10.1016/J.EJPHAR.2011.02.043
P407
P577
2011-03-24T00:00:00Z