Does cellular iron dysregulation play a causative role in Parkinson's disease?
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Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesThe role of oxidative stress in Parkinson's diseaseIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesTransplanted Neural Stem Cells: Playing a Neuroprotective Role by Ceruloplasmin in the Substantia Nigra of PD Model Rats?Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohort.Iron contributes to the formation of catechol isoquinolines and oxidative toxicity induced by overdose dopamine in dopaminergic SH-SY5Y cells.Detection of neuronal loss using T(1rho) MRI assessment of (1)H(2)O spin dynamics in the aphakia mouse.Oxidative inactivation of mitochondrial aconitase results in iron and H2O2-mediated neurotoxicity in rat primary mesencephalic cultures.Intracellular iron transport and storage: from molecular mechanisms to health implications.Late-life hemoglobin and the incidence of Parkinson's disease.Iron and mechanisms of neurotoxicityOxidative stress in neurodegenerationMitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂.The role of environmental exposures in neurodegeneration and neurodegenerative diseases.GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism.Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms.Impact of hydrogen peroxide-driven Fenton reaction on mouse oocyte quality.Impaired iron status in aging researchChelators in the treatment of iron accumulation in Parkinson's disease.Redox imbalance in Parkinson's disease.Lateral Asymmetry and Spatial Difference of Iron Deposition in the Substantia Nigra of Patients with Parkinson Disease Measured with Quantitative Susceptibility MappingFrequency of Hereditary Hemochromatosis (HFE) Gene Mutations in Egyptian Beta Thalassemia Patients and its Relation to Iron Overload.Effects of hemochromatosis and transferrin gene mutations on peripheral iron dyshomeostasis in mild cognitive impairment and Alzheimer's and Parkinson's diseases.Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive elementNutraceuticals against Neurodegeneration: A Mechanistic Insight.SOD2 in mitochondrial dysfunction and neurodegeneration.Iron Chelators as Potential Therapeutic Agents for Parkinson's DiseaseCalorie restriction down-regulates expression of the iron regulatory hormone hepcidin in normal and D-galactose-induced aging mouse brain.The emerging role of iron dyshomeostasis in the mitochondrial decay of aging.The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's diseaseHypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by "antioxidant" metal chelators: From ferroptosis to stroke.Hypoxic Adaptation in the Nervous System: Promise for Novel Therapeutics for Acute and Chronic Neurodegeneration.In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation.A case of hereditary haemochromatosis in a patient with extrapyramidal syndrome.Iron-generated hydroxyl radicals kill retinal cells in vivo: effect of ferulic acid.Nutritional habits, risk, and progression of Parkinson disease.Multiple System Atrophy: Many Lessons from the Transcriptome.Transcriptome analysis of grey and white matter cortical tissue in multiple system atrophy.Magnesium deficiency over generations in rats with special references to the pathogenesis of the Parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam.Blood donations, iron stores, and risk of Parkinson's disease
P2860
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P2860
Does cellular iron dysregulation play a causative role in Parkinson's disease?
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Does cellular iron dysregulation play a causative role in Parkinson's disease?
@ast
Does cellular iron dysregulation play a causative role in Parkinson's disease?
@en
type
label
Does cellular iron dysregulation play a causative role in Parkinson's disease?
@ast
Does cellular iron dysregulation play a causative role in Parkinson's disease?
@en
prefLabel
Does cellular iron dysregulation play a causative role in Parkinson's disease?
@ast
Does cellular iron dysregulation play a causative role in Parkinson's disease?
@en
P1476
Does cellular iron dysregulation play a causative role in Parkinson's disease?
@en
P2093
Deepinder Kaur
Julie Andersen
P304
P356
10.1016/J.ARR.2004.01.003
P577
2004-07-01T00:00:00Z