Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes.
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Development of Human Membrane Transporters: Drug Disposition and PharmacogeneticsDevelopment of biomarkers to optimize pediatric patient management: what makes children different?Pediatric Statin Administration: Navigating a Frontier with Limited DataPharmacogenetics of OATP transporters reveals that SLCO1B1 c.388A>G variant is determinant of increased atorvastatin responseMeta-Analysis of the SLCO1B1 c.521T>C Variant Reveals Slight Influence on the Lipid-Lowering Efficacy of Statins.Rational approach to the treatment for heterozygous familial hypercholesterolemia in childhood and adolescence: a review.Pharmacogenetics of response to statinsPharmacogenetics in clinical pediatrics: challenges and strategies.Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs.Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.Pharmacogenomics of high-density lipoprotein-cholesterol-raising therapies.Clinical response to statins: mechanism(s) of variable activity and adverse effects.Pediatric pharmacogenomics: a systematic assessment of ontogeny and genetic variation to guide the design of statin studies in children.Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy.Mixed effects of OATP1B1, BCRP and NTCP polymorphisms on the population pharmacokinetics of pravastatin in healthy volunteers.Impact of OATP1B1, MDR1, and CYP3A4 expression in liver and intestine on interpatient pharmacokinetic variability of atorvastatin in obese subjects.Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential.Association between a frequent allele of the gene encoding OATP1B1 and enhanced LDL-lowering response to fluvastatin therapy.Approaches to dyslipidemia treatment in children and adolescents
P2860
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P2860
Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Pharmacokinetics and response ...... f the SLCO1B1 and ABCB1 genes.
@ast
Pharmacokinetics and response ...... f the SLCO1B1 and ABCB1 genes.
@en
type
label
Pharmacokinetics and response ...... f the SLCO1B1 and ABCB1 genes.
@ast
Pharmacokinetics and response ...... f the SLCO1B1 and ABCB1 genes.
@en
prefLabel
Pharmacokinetics and response ...... f the SLCO1B1 and ABCB1 genes.
@ast
Pharmacokinetics and response ...... f the SLCO1B1 and ABCB1 genes.
@en
P2093
P2860
P50
P1476
Pharmacokinetics and response ...... f the SLCO1B1 and ABCB1 genes.
@en
P2093
Kari T Kivistö
Marjatta Antikainen
Mia Hedman
Michel Eichelbaum
Pertti J Neuvonen
P2860
P304
P356
10.1111/J.1365-2125.2006.02643.X
P407
P577
2006-06-01T00:00:00Z