Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix
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The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migrationCoronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposureThe Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesionProteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6Recent Insights into Cell Surface Heparan Sulphate Proteoglycans and CancerMechanosensing via cell-matrix adhesions in 3D microenvironmentsAt the leading edge of three-dimensional cell migrationSyndecan-4 signaling at a glanceRho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular traffickingSyndecans play dual roles as cell adhesion receptors and docking receptorsRole of adhesion receptor trafficking in 3D cell migrationHeparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycansUltrasonic Stimulation of Mouse Skin Reverses the Healing Delays in Diabetes and Aging by Activation of Rac1.Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectinInsights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probeThere Is No Simple Model of the Plasma Membrane OrganizationRegulation of the substrate preference of p190RhoGAP by protein kinase C-mediated phosphorylation of a phospholipid binding siteRac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway.Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liverBi-directional signaling: extracellular matrix and integrin regulation of breast tumor progressionRandom versus directionally persistent cell migrationProtein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1)Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway.Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.Therapeutic ultrasound bypasses canonical syndecan-4 signaling to activate rac1PKD controls αvβ3 integrin recycling and tumor cell invasive migration through its substrate Rabaptin-5.Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4RANTES/CCL5 mediated-biological effects depend on the syndecan-4/PKCα signaling pathwayCoronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking.Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cellsMatrix regulators in neural stem cell functions.Heparan sulfate chain valency controls syndecan-4 function in cell adhesion.Syndecan promotes axon regeneration by stabilizing growth cone migration.Ovulation and extra-ovarian origin of ovarian cancerTumorigenic and adhesive properties of heparanase.Regulation of motility of myogenic cells in filling limb muscle anlagen by Pitx2.Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassemblyDistinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis.Heparan sulfate proteoglycans.
P2860
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P2860
Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix
@ast
Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix
@en
type
label
Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix
@ast
Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix
@en
prefLabel
Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix
@ast
Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix
@en
P2093
P2860
P356
P1476
Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix
@en
P2093
Christoph Ballestrem
Kirsty A Roach
Mark D Bass
Mark R Morgan
Martin J Humphries
Takashi Muramatsu
Tobias Schoen
Ulrike Mayer
Zohreh Mostafavi-Pour
P2860
P304
P356
10.1083/JCB.200610076
P407
P577
2007-05-01T00:00:00Z