Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix - Wikidata - awgldk - TriplyDB

Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix

Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix

http://www.wikidata.org/entity/Q35828567

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The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migration Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6 Recent Insights into Cell Surface Heparan Sulphate Proteoglycans and Cancer Mechanosensing via cell-matrix adhesions in 3D microenvironments At the leading edge of three-dimensional cell migration Syndecan-4 signaling at a glance Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking Syndecans play dual roles as cell adhesion receptors and docking receptors Role of adhesion receptor trafficking in 3D cell migration Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans Ultrasonic Stimulation of Mouse Skin Reverses the Healing Delays in Diabetes and Aging by Activation of Rac1.Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe There Is No Simple Model of the Plasma Membrane Organization Regulation of the substrate preference of p190RhoGAP by protein kinase C-mediated phosphorylation of a phospholipid binding site Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway.Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression Random versus directionally persistent cell migration Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1)Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway.Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.Therapeutic ultrasound bypasses canonical syndecan-4 signaling to activate rac1 PKD controls αvβ3 integrin recycling and tumor cell invasive migration through its substrate Rabaptin-5.Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4 RANTES/CCL5 mediated-biological effects depend on the syndecan-4/PKCα signaling pathway Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking.Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cells Matrix regulators in neural stem cell functions.Heparan sulfate chain valency controls syndecan-4 function in cell adhesion.Syndecan promotes axon regeneration by stabilizing growth cone migration.Ovulation and extra-ovarian origin of ovarian cancer Tumorigenic and adhesive properties of heparanase.Regulation of motility of myogenic cells in filling limb muscle anlagen by Pitx2.Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis.Heparan sulfate proteoglycans.

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P2860

Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix

http://www.wikidata.org/entity/Q35828567

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix

@ast

Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix

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type

label

Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix

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Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix

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prefLabel

Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix

@ast

Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix

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P1433

Journal of Cell Biology

P1476

Syndecan-4-dependent Rac1 regu ...... se to the extracellular matrix

@en

P2093

Christoph Ballestrem

http://www.w3.org/2001/XMLSchema#string

Kirsty A Roach

http://www.w3.org/2001/XMLSchema#string

Mark D Bass

http://www.w3.org/2001/XMLSchema#string

Mark R Morgan

http://www.w3.org/2001/XMLSchema#string

Martin J Humphries

http://www.w3.org/2001/XMLSchema#string

Takashi Muramatsu

http://www.w3.org/2001/XMLSchema#string

Tobias Schoen

http://www.w3.org/2001/XMLSchema#string

Ulrike Mayer

http://www.w3.org/2001/XMLSchema#string

Zohreh Mostafavi-Pour

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of a heparin- and integrin-binding segment of human fibronectin.

Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha

Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling

Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component

Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4

Rho and Rac take center stage

Comparative genomics of the syndecans defines an ancestral genomic context associated with matrilins in vertebrates

Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis

Activation of Rac and Cdc42 by integrins mediates cell spreading

Cell migration: Rho GTPases lead the way

P304

527-538

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scholarly article

P356

10.1083/JCB.200610076

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P407

P433

3

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P478

177

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Joachim P. Spatz

P577

2007-05-01T00:00:00Z

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P5875

6346908

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P698

17485492

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P921

extracellular matrix

P932

1885470

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