Platelet glycoprotein Ib alpha supports experimental lung metastasis
about
Mechanisms of bone metastases of breast cancerDeadly allies: the fatal interplay between platelets and metastasizing cancer cellsMegakaryocytes, malignancy and bone marrow vascular nichesJuxtamembrane basic residues in glycoprotein Ibbeta cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex.Platelet P2Y12 is involved in murine pulmonary metastasisPlatelet granule secretion continuously prevents intratumor hemorrhage.Proteolysis of platelet receptors in humans and other species.Platelets in pulmonary vascular physiology and pathology.NF-E2 p45 is important for establishing normal function of platelets.Role for platelet glycoprotein Ib-IX and effects of its inhibition in endotoxemia-induced thrombosis, thrombocytopenia, and mortality.Living in shear: platelets protect cancer cells from shear induced damage.Platelets in liver disease, cancer and regenerationVisualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation.Tissue factor and PAR2 signaling in the tumor microenvironmentIntegrated analysis of genes associated with poor prognosis of patients with colorectal cancer liver metastasis.Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis.Bone metastasis: mechanisms and therapeutic opportunities.Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells.The organizing principle of the platelet glycoprotein Ib-IX-V complex.Current concepts of metastasis in melanoma.The physics of cancer: the role of physical interactions and mechanical forces in metastasis.Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 integrin mediates interaction of melanoma cells with platelets: a connection to hematogenous metastasis.Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis.A humanized single-chain antibody against beta 3 integrin inhibits pulmonary metastasis by preferentially fragmenting activated platelets in the tumor microenvironment.The challenge of targeting metastasis.Changes in neutrophil/lymphocyte and platelet/lymphocyte ratios after chemotherapy correlate with chemotherapy response and prediction of prognosis in patients with unresectable gastric cancer.Platelets increase the proliferation of ovarian cancer cellsSignaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activationA functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complexInhibition of MCF-7 breast cancer cell-induced platelet aggregation using a combination of antiplatelet drugs.The metastatic niche: adapting the foreign soil.The role of platelet activation in tumor metastasis.Platelet alpha-granules: basic biology and clinical correlates.Activated platelets inhibit hepatocellular carcinoma cell differentiation and promote tumor progression via platelet-tumor cell binding.The platelet contribution to cancer progression.Platelet physiology and antiplatelet agents.Platelets: linking hemostasis and cancer.Tissue factor and cell signalling in cancer progression and thrombosis.Tissue factor and cancer.The functional role of platelets in the regulation of angiogenesis.
P2860
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P2860
Platelet glycoprotein Ib alpha supports experimental lung metastasis
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Platelet glycoprotein Ib alpha supports experimental lung metastasis
@ast
Platelet glycoprotein Ib alpha supports experimental lung metastasis
@en
type
label
Platelet glycoprotein Ib alpha supports experimental lung metastasis
@ast
Platelet glycoprotein Ib alpha supports experimental lung metastasis
@en
prefLabel
Platelet glycoprotein Ib alpha supports experimental lung metastasis
@ast
Platelet glycoprotein Ib alpha supports experimental lung metastasis
@en
P2093
P2860
P356
P1476
Platelet glycoprotein Ib alpha supports experimental lung metastasis
@en
P2093
Brigid Maruszak
Brunhilde Felding-Habermann
Jane Forsyth
Jerry Ware
José A Guerrero
Judith Dent
Jungling Liu
Masahiko Zuka
Shashank Jain
Susan Russell
P2860
P304
P356
10.1073/PNAS.0700625104
P407
P577
2007-05-09T00:00:00Z