Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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Nanoprobes for Multimodal Visualization of Bone Mineral Phase in Magnetic Resonance and Near-Infrared Optical Imaging.

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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2014 nî lūn-bûn

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2014年論文

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2014年論文

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2014年論文

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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P1476

Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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Andrea Visconti

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Chao Yan

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David Ross

http://www.w3.org/2001/XMLSchema#string

David Siegel

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Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches

Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein Inhibition

Hypoxia-selective activation of 5-fluorodeoxyuridine prodrug possessing indolequinone structure: radiolytic reduction and cytotoxicity characteristics.

The synthesis of a c(RGDyK) targeted SN38 prodrug with an indolequinone structure for bioreductive drug release.

Antitumor indolequinones induced apoptosis in human pancreatic cancer cells via inhibition of thioredoxin reductase and activation of redox signaling.

EO9 (Apaziquone): from the clinic to the laboratory and back again

Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential.

Potent activity of indolequinones against human pancreatic cancer: identification of thioredoxin reductase as a potential target.

Discorhabdins and pyrroloiminoquinone-related alkaloids.

Drugs in preclinical and early-stage clinical development for pancreatic cancer.

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4848-4861

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scholarly article

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10.1039/C4OB00711E

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P478

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Christopher J. Moody

Martyn Inman

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2014-07-01T00:00:00Z

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24848343

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4495957

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells

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P1476

P2093

P2860

P304

P31

P356

P433

P478

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P577

P698

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P433

P478

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P577

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