K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.

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Genetic determinants and potential therapeutic targets for pancreatic adenocarcinoma MicroRNAs: control and loss of control in human physiology and disease Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer Recent progress in pancreatic cancer Genetic mutations associated with cigarette smoking in pancreatic cancer What is the origin of pancreatic adenocarcinoma?The role of transgenic mouse models in carcinogen identification Pancreatic Cancer from Molecular Pathways to Treatment Opinion Molecular targets for the treatment of pancreatic cancer: Clinical and experimental studies Imaging and Therapy of Pancreatic Cancer with Phosphatidylserine-Targeted Nanovesicles Heterogeneity and targeting of pancreatic cancer stem cells Interplay between smoking-induced genotoxicity and altered signaling in pancreatic carcinogenesis Somatic mutations in exocrine pancreatic tumors: association with patient survival Genetic factors affecting patient responses to pancreatic cancer treatment KRAS mutant allele-specific imbalance is associated with worse prognosis in pancreatic cancer and progression to undifferentiated carcinoma of the pancreas Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein Allele specific locked nucleic acid quantitative PCR (ASLNAqPCR): an accurate and cost-effective assay to diagnose and quantify KRAS and BRAF mutation The immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors.A phase I study of sorafenib, oxaliplatin and 2 days of high dose capecitabine in advanced pancreatic and biliary tract cancer: a Wisconsin oncology network study.KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin Pathology and molecular genetics of pancreatic neoplasms.Pancreatic adenocarcinoma: epidemiology and genetics.MGMT promoter hypermethylation and K-RAS, PTEN and TP53 mutations in tamoxifen-exposed and non-exposed endometrial cancer cases Comparative analysis of clinicopathological correlations of cyclooxygenase-2 expression in resectable pancreatic cancer Epigenetics and pancreatic cancer: pathophysiology and novel treatment aspects Pancreatic cancer: any prospects for prevention?A rapid PCR ELISA for the detection of activated K-ras in colorectal cancer.KRAS mutational analysis and immunohistochemical studies can help distinguish pancreatic metastases from primary lung adenocarcinomas.Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation.BITC Sensitizes Pancreatic Adenocarcinomas to TRAIL-induced Apoptosis Molecular signatures of pancreatic cancer.Genetic progression in the pancreatic ducts.Clinical relevance of KRAS in human cancers.In vitro and in vivo activity of novel small-molecule inhibitors targeting the pleckstrin homology domain of protein kinase B/AKT.Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors.Chemoprevention strategies for pancreatic cancer Complex role for the immune system in initiation and progression of pancreatic cancer.Ras in cancer and developmental diseases The molecular targets for the diagnosis and treatment of pancreatic cancer.Phenotypic changes in mouse pancreatic stellate cell Ca2+ signaling events following activation in culture and in a disease model of pancreatitis.

P2860

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P2860

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.

Item

http://www.wikidata.org/entity/Q35833155

description

1993 nî lūn-bûn

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1993年論文

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1993年論文

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1993年論文

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1993年论文

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1993年论文

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P2860

Genetic alterations during colorectal-tumor development

Pancreatic cancer, alcohol, diabetes mellitus and gall-bladder disease

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

ras oncogenes in human cancer: a review

ras genes

Identification of p53 gene mutations in bladder cancers and urine samples.

Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines.

v-rasH induces non-small cell phenotype, with associated growth factors and receptors, in a small cell lung cancer cell line.

Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors.

Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors.

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adenocarcinoma

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1887038

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K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.

about

P2860

P2860

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.

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