UGT1A1 is a major locus influencing bilirubin levels in African Americans.
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir PrescribingGenetics of human metabolism: an updateComparative Analyses of QTLs Influencing Obesity and Metabolic Phenotypes in Pigs and HumansTrans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations.Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.Genome-wide discovery of drug-dependent human liver regulatory elementsGenomewide association study of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials Group protocol A5202.Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects.Insight in genome-wide association of metabolite quantitative traits by exome sequence analysesGenome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortiumGenome-wide analysis of hepatic lipid content in extreme obesityGenome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease.A GWAS Study on Liver Function Test Using eMERGE Network ParticipantsSerum bilirubin concentration is modified by UGT1A1 haplotypes and influences risk of type-2 diabetes in the Norfolk Island genetic isolate.C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans.Exome-Wide Association Study Identifies New Low-Frequency and Rare UGT1A1 Coding Variants and UGT1A6 Coding Variants Influencing Serum Bilirubin in Elderly Subjects: A Strobe Compliant ArticleEvaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans.Fine-mapping of the 6q25 locus identifies a novel SNP associated with breast cancer risk in African-American womenWhy personalized medicine will fail if we stay the course.Comprehensive variant screening of the UGT gene familyCase-Control Genome-wide Joint Association Study Using Semiparametric Empirical Model and Approximate Bayes Factor.Idiosyncratic Drug-Induced Liver Injury (IDILI): Potential Mechanisms and Predictive Assays.Accounting for linkage disequilibrium in association analysis of diverse populations.Role of pharmacogenetics on deferasirox AUC and efficacy.Hyperbilirubinemia in atazanavir treated HIV-infected patients: the impact of the UGT1A1*28 allele.Influence of single-nucleotide polymorphisms on deferasirox C trough levels and effectiveness.A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockersA genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.Mice with hyperbilirubinemia due to Gilbert's syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPARα.
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P2860
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
@ast
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
@en
type
label
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
@ast
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
@en
prefLabel
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
@ast
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
@en
P2093
P2860
P50
P356
P1476
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
@en
P2093
Alan Herbert
Amy R Bentley
Ayo P Doumatey
Bashira A Charles
Edward Ramos
Guanjie Chen
Hanxia Huang
Huichun Xu
Michael F Christman
P2860
P2888
P304
P356
10.1038/EJHG.2011.206
P577
2011-11-16T00:00:00Z
P5875
P6179
1001665615