Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice. - Wikidata - awgldk - TriplyDB

Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.

Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.

http://www.wikidata.org/entity/Q35838871

about

Nutrition and the risk of Alzheimer's disease Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice Electromagnetic treatment to old Alzheimer's mice reverses β-amyloid deposition, modifies cerebral blood flow, and provides selected cognitive benefit Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer's disease.Protective effects of gingerol on streptozotocin-induced sporadic Alzheimer's disease: emphasis on inhibition of β-amyloid, COX-2, alpha-, beta - secretases and APH1a Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice.Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ42 by reducing plaque load and motor deficit Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects Tannic acid inhibits EGFR/STAT1/3 and enhances p38/STAT1 signalling axis in breast cancer cells.Polyphenols: multipotent therapeutic agents in neurodegenerative diseases.Cognitive impairment in gynecologic cancers: a systematic review of current approaches to diagnosis and treatment.Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease.Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer's disease pathophysiology.Inhibition of amyloid oligomerization into different supramolecular architectures by small molecules: mechanistic insights and design rules.Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.A Novel, Multi-Target Natural Drug Candidate, Matrine, Improves Cognitive Deficits in Alzheimer's Disease Transgenic Mice by Inhibiting Aβ Aggregation and Blocking the RAGE/Aβ Axis.Dietary Modulation of Oxidative Stress in Alzheimer's Disease.Bioappearance and pharmacokinetics of bioactives upon coffee consumption.Spatial learning impairments in PLB1Triple knock-in Alzheimer mice are task-specific and age-dependent.Biomimetic-Functionalized, Tannic Acid-Templated Mesoporous Silica as a New Support for Immobilization of NHase.Microencapsulation of tannic acid for oral administration to inhibit carbohydrate digestion in the gastrointestinal tract.Impact of Flavonoids on Cellular and Molecular Mechanisms Underlying Age-Related Cognitive Decline and Neurodegeneration.Byssal threads inspired ionic cross-linked narce-like graphene oxide paper with superior mechanical strength Polyphenols and brain health

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P2860

Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.

http://www.wikidata.org/entity/Q35838871

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Tannic acid is a natural β-sec ...... pathology in transgenic mice.

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Tannic acid is a natural β-sec ...... pathology in transgenic mice.

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type

label

Tannic acid is a natural β-sec ...... pathology in transgenic mice.

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Tannic acid is a natural β-sec ...... pathology in transgenic mice.

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Tannic acid is a natural β-sec ...... pathology in transgenic mice.

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Tannic acid is a natural β-sec ...... pathology in transgenic mice.

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Journal of Biological Chemistry

P1476

Tannic acid is a natural β-sec ...... pathology in transgenic mice.

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P2093

Gary W Arendash

http://www.w3.org/2001/XMLSchema#string

Haruyasu Yamaguchi

http://www.w3.org/2001/XMLSchema#string

Jun Tan

http://www.w3.org/2001/XMLSchema#string

Kavon Rezai-Zadeh

http://www.w3.org/2001/XMLSchema#string

Naoki Koyama

http://www.w3.org/2001/XMLSchema#string

Nobuto Kakuda

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Takashi Mori

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Terrence Town

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Yuko Horikoshi-Sakuraba

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P2860

Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Alzheimer's disease: genes, proteins, and therapy

Inflammation and Alzheimer's disease

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT

A specific amyloid-beta protein assembly in the brain impairs memory

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6912-6927

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22219198

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Alzheimer's disease

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