Transgenic mice with SCA10 pentanucleotide repeats show motor phenotype and susceptibility to seizure: a toxic RNA gain-of-function model.
about
Altered ribostasis: RNA-protein granules in degenerative disordersRepeat interruptions in spinocerebellar ataxia type 10 expansions are strongly associated with epileptic seizuresSMRT Sequencing of Long Tandem Nucleotide Repeats in SCA10 Reveals Unique Insight of Repeat Expansion StructureRNA-binding protein misregulation in microsatellite expansion disordersBolivian kindred with combined spinocerebellar ataxia types 2 and 10.First report of a Japanese family with spinocerebellar ataxia type 10: The second report from Asia after a report from ChinaIdentifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases.Transgenic models of spinocerebellar ataxia type 10: modeling a repeat expansion disorder.Consensus paper: pathological mechanisms underlying neurodegeneration in spinocerebellar ataxias.Pre-mRNA splicing in disease and therapeutics.The autosomal dominant spinocerebellar ataxias: emerging mechanistic themes suggest pervasive Purkinje cell vulnerability.Heterogeneous nuclear ribonucleoprotein K supports vesicular stomatitis virus replication by regulating cell survival and cellular gene expressionProtein sequestration as a normal function of long noncoding RNAs and a pathogenic mechanism of RNAs containing nucleotide repeat expansions.Paradoxical effects of repeat interruptions on spinocerebellar ataxia type 10 expansions and repeat instability.Purkinje cell loss is the major brain pathology of spinocerebellar ataxia type 10.Aurora B-dependent phosphorylation of Ataxin-10 promotes the interaction between Ataxin-10 and Plk1 in cytokinesis.Polyglutamine spinocerebellar ataxias - from genes to potential treatments.
P2860
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P2860
Transgenic mice with SCA10 pentanucleotide repeats show motor phenotype and susceptibility to seizure: a toxic RNA gain-of-function model.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Transgenic mice with SCA10 pen ...... ic RNA gain-of-function model.
@ast
Transgenic mice with SCA10 pen ...... ic RNA gain-of-function model.
@en
type
label
Transgenic mice with SCA10 pen ...... ic RNA gain-of-function model.
@ast
Transgenic mice with SCA10 pen ...... ic RNA gain-of-function model.
@en
prefLabel
Transgenic mice with SCA10 pen ...... ic RNA gain-of-function model.
@ast
Transgenic mice with SCA10 pen ...... ic RNA gain-of-function model.
@en
P2093
P2860
P356
P1476
Transgenic mice with SCA10 pen ...... ic RNA gain-of-function model.
@en
P2093
Guangbin Xia
Karen McFarland
Maki Wakamiya
Misti White
Partha S Sarkar
Tetsuo Ashizawa
P2860
P304
P356
10.1002/JNR.22786
P577
2011-11-08T00:00:00Z