Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease - Wikidata - awgldk - TriplyDB

Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease

Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease

http://www.wikidata.org/entity/Q35839636

about

Apolipoprotein E receptors in the nervous system Wnt modulators in the biotech pipeline Signaling mechanisms regulating adult neural stem cells and neurogenesis A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation Endophenotypes in normal brain morphology and Alzheimer's disease: a review Genetics of coronary artery disease and myocardial infarction Wnts in action: from synapse formation to synaptic maintenance Erythropoietin: new directions for the nervous system Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease The regulation and deregulation of Wnt signaling by PARK genes in health and disease Wnt signaling in the vertebrate central nervous system: from axon guidance to synaptic function.Wnt signaling in neuropsychiatric disorders: ties with adult hippocampal neurogenesis and behavior Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice Structural and Functional Studies of LRP6 Ectodomain Reveal a Platform for Wnt Signaling LRP5 and LRP6 in development and disease Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma The importance of Wnt signalling for neurodegeneration in Parkinson's disease Canonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neurons RoR2 functions as a noncanonical Wnt receptor that regulates NMDAR-mediated synaptic transmission Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases.Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.A common biological mechanism in cancer and Alzheimer's disease?A common variant in low-density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-cholesterol The role of Wnt signaling in the development of Alzheimer's disease: a potential therapeutic target?Use of genetic variation as biomarkers for Alzheimer's disease.Decreased Circulating Levels of Dickkopf-1 in Patients with Exudative Age-related Macular Degeneration Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.The LRP6 rs2302685 polymorphism is associated with increased risk of myocardial infarction.Wnt Signaling in Neurogenesis during Aging and Physical Activity.Wnt/β-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells.Wnt1, FoxO3a, and NF-kappaB oversee microglial integrity and activation during oxidant stress.WNT5A signaling contributes to Aβ-induced neuroinflammation and neurotoxicity.Use of genetic variation as biomarkers for mild cognitive impairment and progression of mild cognitive impairment to dementia.Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathology Association of a functional variant in the Wnt co-receptor LRP6 with early onset ileal Crohn's disease Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways.Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease.

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P2860

Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease

http://www.wikidata.org/entity/Q35839636

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Common genetic variation withi ...... late-onset Alzheimer's disease

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Common genetic variation withi ...... late-onset Alzheimer's disease

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type

label

Common genetic variation withi ...... late-onset Alzheimer's disease

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Common genetic variation withi ...... late-onset Alzheimer's disease

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prefLabel

Common genetic variation withi ...... late-onset Alzheimer's disease

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Common genetic variation withi ...... late-onset Alzheimer's disease

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PNAS.0603523104

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Common genetic variation withi ...... late-onset Alzheimer's disease

@en

P2093

Alice Zhao

http://www.w3.org/2001/XMLSchema#string

Amanda Myers

http://www.w3.org/2001/XMLSchema#string

Andreas Papassotiropoulos

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Chris M Morris

http://www.w3.org/2001/XMLSchema#string

Christoph Hock

http://www.w3.org/2001/XMLSchema#string

Fabienne Wavrant De-Vrieze

http://www.w3.org/2001/XMLSchema#string

Giancarlo V De Ferrari

http://www.w3.org/2001/XMLSchema#string

Juan P Henríquez

http://www.w3.org/2001/XMLSchema#string

Katia Sáez

http://www.w3.org/2001/XMLSchema#string

M Axel Wollmer

http://www.w3.org/2001/XMLSchema#string

P2860

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

LDL-receptor-related proteins in Wnt signal transduction

Wnt genes define distinct boundaries in the developing human brain: implications for human forebrain patterning

Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

A novel mammalian wnt gene, WNT8B, shows brain-restricted expression in early development, with sharply delimited expression boundaries in the developing forebrain

Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

The International HapMap Project

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9434-9439

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scholarly article

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10.1073/PNAS.0603523104

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22

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104

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John Anthony Hardy

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2007-05-21T00:00:00Z

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6314290

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17517621

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Alzheimer's disease

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1890512

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