Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction
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The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingThe current view for the silencing of the spindle assembly checkpointAurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindleEB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule latticeThe molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling.Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain.The kinetochore-bound Ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments.Structural basis for microtubule recognition by the human kinetochore Ska complexMechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores.Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Multimodal microtubule binding by the Ndc80 kinetochore complex.Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?The kinetochoreAn integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes.How chromosome mis-segregation leads to cancer: lessons from BubR1 mouse modelsThe KMN protein network--chief conductors of the kinetochore orchestraThe internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment.New insights into the mechanism for chromosome alignment in metaphaseMaking an effective switch at the kinetochore by phosphorylation and dephosphorylation.The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis.The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit.Mitosis puts sisters in a strained relationship: force generation at the kinetochore.Regulatory mechanisms of kinetochore-microtubule interaction in mitosis.Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.Dynamic regulation of kinetochore-microtubule interaction during mitosis.Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore.Linked in: formation and regulation of microtubule attachments during chromosome segregation.Differentiating the roles of microtubule-associated proteins at meiotic kinetochores during chromosome segregation.Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression.A Molecular View of Kinetochore Assembly and Function.Kinetochore assembly and function through the cell cycle.EBNA3C regulates p53 through induction of Aurora kinase B.SKA1 over-expression promotes centriole over-duplication, centrosome amplification and prostate tumourigenesis.Spindle and kinetochore-associated protein 1 is overexpressed in gastric cancer and modulates cell growth.The Ska complex promotes Aurora B activity to ensure chromosome biorientation.The phosphorylation of a kinetochore protein Dam1 by Aurora B/Ipl1 kinase promotes chromosome bipolar attachment in yeast.Kinetochore-microtubule error correction is driven by differentially regulated interaction modes.Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Checkpoint silencing.Balancing the kinetochore ledger.
P2860
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P2860
Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Aurora B controls kinetochore- ...... omplex-KMN network interaction
@ast
Aurora B controls kinetochore- ...... omplex-KMN network interaction
@en
type
label
Aurora B controls kinetochore- ...... omplex-KMN network interaction
@ast
Aurora B controls kinetochore- ...... omplex-KMN network interaction
@en
prefLabel
Aurora B controls kinetochore- ...... omplex-KMN network interaction
@ast
Aurora B controls kinetochore- ...... omplex-KMN network interaction
@en
P2860
P356
P1476
Aurora B controls kinetochore- ...... omplex-KMN network interaction
@en
P2093
A Arockia Jeyaprakash
Anna Santamaria
P2860
P304
P356
10.1083/JCB.201109001
P407
P577
2012-02-27T00:00:00Z