Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection
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Emerging targets and novel approaches to Ebola virus prophylaxis and treatmentMonoclonal antibodies combined with adenovirus-vectored interferon significantly extend the treatment window in Ebola virus-infected guinea pigsClinical development of Ebola vaccinesMouse models for filovirus infectionsCell-targeting antibodies in immunity to EbolaProduction of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal CattleMapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular EntryIdentification of continuous human B-cell epitopes in the VP35, VP40, nucleoprotein and glycoprotein of Ebola virusReversion of advanced Ebola virus disease in nonhuman primates with ZMappAn update on the use of antibodies against the filoviruses.Structures of protective antibodies reveal sites of vulnerability on Ebola virus.Chemical and Structural Aspects of Ebola Virus Entry Inhibitors.Ebolavirus and Haemorrhagic Syndrome.Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses.Vaccination With a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge With a Lethal Dose of Ebola Virus.Profiling the native specific human humoral immune response to Sudan Ebola virus strain Gulu by chemiluminescence enzyme-linked immunosorbent assay.Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan VirusesMacaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein.Antibodies are necessary for rVSV/ZEBOV-GP-mediated protection against lethal Ebola virus challenge in nonhuman primatesTreatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection.Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding SiteIsolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreakPost-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic.Immune parameters correlate with protection against ebola virus infection in rodents and nonhuman primatesNext Generation Vaccine Biomarkers workshop October 30-31, 2014--Ottawa, Canada.The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies.Modeling pre-existing immunity to adenovirus in rodents: immunological requirements for successful development of a recombinant adenovirus serotype 5-based ebola vaccine.Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus.Development of experimental and early investigational drugs for the treatment of Ebola virus infections.Recombinant Modified Vaccinia Virus Ankara Generating Ebola Virus-Like Particles.Modeling the Disease Course of Zaire ebolavirus Infection in the Outbred Guinea Pig.Therapeutics for postexposure treatment of Ebola virus infection.Assessing Antiviral Countermeasures Using Mouse Models of Ebolavirus Infection.Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus.Therapeutics Against Filovirus Infection.mAbs and Ad-vectored IFN-α therapy rescue Ebola-infected nonhuman primates when administered after the detection of viremia and symptoms.Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies.In Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections.Assessment of the ability of V920 recombinant vesicular stomatitis-Zaire ebolavirus vaccine to replicate in relevant arthropod cell cultures and vector species.Passive immunotherapy of viral infections: 'super-antibodies' enter the fray.
P2860
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P2860
Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Ebola GP-specific monoclonal a ...... m lethal Ebola virus infection
@ast
Ebola GP-specific monoclonal a ...... m lethal Ebola virus infection
@en
type
label
Ebola GP-specific monoclonal a ...... m lethal Ebola virus infection
@ast
Ebola GP-specific monoclonal a ...... m lethal Ebola virus infection
@en
prefLabel
Ebola GP-specific monoclonal a ...... m lethal Ebola virus infection
@ast
Ebola GP-specific monoclonal a ...... m lethal Ebola virus infection
@en
P2093
P2860
P50
P921
P1476
Ebola GP-specific monoclonal a ...... m lethal Ebola virus infection
@en
P2093
Judie B Alimonti
Lisa Fernando
P Leno Melito
Steven M Jones
P2860
P356
10.1371/JOURNAL.PNTD.0001575
P407
P5008
P577
2012-03-20T00:00:00Z