Potentiation of ghrelin signaling attenuates cancer anorexia-cachexia and prolongs survival.
about
Cancer cachexia--pathophysiology and managementGhrelin for the management of cachexia associated with cancerCancer as a Proinflammatory Environment: Metastasis and CachexiaThe translational aspect of complementary and alternative medicine for cancer with particular emphasis on KampoKampo medicines for gastrointestinal tract disorders: a review of basic science and clinical evidence and their future applicationClinical characteristics of elderly patients with proton pump inhibitor-refractory non-erosive reflux disease from the G-PRIDE study who responded to rikkunshito.Clinical development of ghrelin axis-derived molecules for cancer cachexia treatmentAltered ghrelin secretion in mice in response to diet-induced obesity and Roux-en-Y gastric bypass.Enhancement of catecholamine release from PC12 cells by the traditional Japanese medicine, rikkunshito.Rikkunshito, a ghrelin potentiator, ameliorates anorexia-cachexia syndromeCancer cachexia, mechanism and treatmentAdministration of exogenous acylated ghrelin or rikkunshito, an endogenous ghrelin enhancer, improves the decrease in postprandial gastric motility in an acute restraint stress mouse model.A New Strategy Using Rikkunshito to Treat Anorexia and Gastrointestinal DysfunctionInsulin suppresses ghrelin-induced calcium signaling in neuropeptide Y neurons of the hypothalamic arcuate nucleusPharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study.Rikkunshito Ameliorates Cancer Cachexia Partly through Elevation of Glucarate in PlasmaDevelopment of ghrelin resistance in a cancer cachexia rat model using human gastric cancer-derived 85As2 cells and the palliative effects of the Kampo medicine rikkunshito on the model.Rikkunshito improves globus sensation in patients with proton-pump inhibitor-refractory laryngopharyngeal refluxIncreased Ghrelin but Low Ghrelin-Reactive Immunoglobulins in a Rat Model of Methotrexate Chemotherapy-Induced Anorexia.β1-Adrenergic receptor deficiency in ghrelin-expressing cells causes hypoglycemia in susceptible individuals.Characteristics of gastrointestinal symptoms and function following endoscopic submucosal dissection and treatment of the gastrointestinal symptoms using rikkunshito.Intracerebroventricular urocortin 3 counteracts central acyl ghrelin-induced hyperphagic and gastroprokinetic effects via CRF receptor 2 in rats.Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin1.Effects of Kampo on functional gastrointestinal disorders.Beneficial effects of rikkunshito, a Japanese kampo medicine, on gastrointestinal dysfunction and anorexia in combination with Western drug: a systematic review.Therapeutic applications of ghrelin agonists in the treatment of gastroparesis.Developing models for cachexia and their implications in drug discovery.Anorexia in human and experimental animal models: physiological aspects related to neuropeptides.Additive effect of rikkunshito, an herbal medicine, on chemotherapy-induced nausea, vomiting, and anorexia in uterine cervical or corpus cancer patients treated with cisplatin and paclitaxel: results of a randomized phase II study (JORTC KMP-02).New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line.α-melanocyte stimulating hormone modulates the central acyl ghrelin-induced stimulation of feeding, gastrointestinal motility, and colonic secretion.Atractylodin Induces Myosin Light Chain Phosphorylation and Promotes Gastric Emptying through Ghrelin Receptor.Open Label Trial of the Efficacy and Safety Profile of Rikkunshito used for the Treatment of Gastrointestinal Symptoms in Patients with Parkinson's Disease: A Pilot Study.Rikkunshito, a Japanese kampo medicine, ameliorates decreased feeding behavior via ghrelin and serotonin 2B receptor signaling in a novelty stress murine model.Impaired ghrelin signaling is associated with gastrointestinal dysmotility in rats with gastroesophageal reflux disease.Preventive effect of rikkunshito on gastric motor function inhibited by L-dopa in rats.Psychological stress in aged female mice causes acute hypophagia independent of central serotonin 2C receptor activation.Ghrelin as a Survival Hormone.Influence of food on the gastric motor effect of the Kampo medicine rikkunshito in rat.A randomized, placebo-controlled, double-blind clinical trial of rikkunshito for patients with non-erosive reflux disease refractory to proton-pump inhibitor: the G-PRIDE study.
P2860
Q24605567-6B70F8EA-937A-4CB1-992C-D281143B2872Q26471773-5CA21EED-2396-4B2E-B804-F122088CA609Q26778324-2FF0B7FC-B0E6-4770-B818-E265D61C19C6Q26795520-63E39836-1044-4F84-9206-5C7C4281C873Q26830898-888CBF7D-06DC-443C-9576-7089E5A2FD83Q31170383-B984028A-2C60-42A9-B0D0-BBF9D5CFE782Q34002674-BD6524FD-F2B1-4F4D-AF7E-9A1FAB43D530Q34404065-EC63ED0F-2785-466B-B9F4-DE5DAE2D4E2AQ34468971-FE7A61CB-8198-4C17-BD23-92CA8EA1B94DQ34669261-EE32D495-BBCB-469C-B834-E14BD87A899CQ34669440-9F9AB6DD-43AA-49CA-A8D5-42AC070ECC7BQ35556669-3E7560D6-D4A5-4E36-B0A6-F008CB7E08AEQ35612563-0E584E67-E004-4985-9BBC-2FA4ADF6ADAEQ35645155-BBC6F2B2-971B-41F8-BBED-BF3A667CE9AAQ35694926-FB981EBA-4833-4DBD-8EC1-9F87BE66665CQ36103348-19E325AD-2CDC-42BE-BFBC-B42A2572C94DQ36294093-27032664-22C6-43BA-A5C3-8A4A5F1C1533Q37102475-5E9554CA-203E-4552-8443-7D726C3E053FQ37124526-BDF50828-603A-40B5-AEDC-411ACB3689DFQ37217540-B618B1E3-C87F-4F1A-B277-6613BCD6BE08Q37288757-51CF95F5-62E7-4D30-A6A0-B82735EE9F2EQ37320958-9721E73A-B742-4B43-B513-BE59FEA013AAQ37364108-47D138D0-9720-4D12-B33C-53FF0ACC8CE5Q37532337-7C4AAD50-E916-44CE-8518-C7C06F838067Q37691031-15A3C124-CACE-4ACD-9CAE-A8EFDD73D7BEQ38363587-98174103-A216-46C3-AF2C-28BF750734D1Q38451282-62CBD653-6145-4CE1-936D-01006B3DF2C4Q38540231-E3953E55-2B7D-4CEA-BA5F-BA2B33A77E93Q38705385-C1DE4F9A-FE8F-4486-AC03-AAA025C1B718Q39042463-B432CC81-EF59-42DC-B15F-5BC975AEF965Q41483608-BFFFF845-5E5B-4C17-8E4F-E5332B2D9C79Q41528767-EF369C14-F6FF-46B6-BC2C-F25D4E652149Q41605478-2062BE6B-DA45-443A-9DC8-23F4D4DCB297Q41965543-545B48F4-019E-4BCA-ADEA-73777398CAE2Q42053790-A48A2199-71BD-4F29-8418-7B851D1D142DQ43685308-3D23F2DF-96FF-41A4-9BE4-C63030CCD8DDQ47118191-68737A80-3417-431E-979E-3ADD9AC5163DQ47721194-AFA4892F-BBAB-4818-9967-807F113BB16AQ48056563-D52D03B1-CCFF-4DE6-B454-17C5DF9653B6Q48085570-7199EE45-9DF6-42FC-A7AB-85A63CE04BB9
P2860
Potentiation of ghrelin signaling attenuates cancer anorexia-cachexia and prolongs survival.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Potentiation of ghrelin signal ...... achexia and prolongs survival.
@ast
Potentiation of ghrelin signal ...... achexia and prolongs survival.
@en
type
label
Potentiation of ghrelin signal ...... achexia and prolongs survival.
@ast
Potentiation of ghrelin signal ...... achexia and prolongs survival.
@en
prefLabel
Potentiation of ghrelin signal ...... achexia and prolongs survival.
@ast
Potentiation of ghrelin signal ...... achexia and prolongs survival.
@en
P2093
P2860
P356
P1476
Potentiation of ghrelin signal ...... achexia and prolongs survival.
@en
P2093
N Fujitsuka
T Yamaguchi
U Sedbazar
P2860
P2888
P356
10.1038/TP.2011.25
P577
2011-07-26T00:00:00Z