about
Antischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoniSafety and immunogenicity of rSh28GST antigen in humans: phase 1 randomized clinical study of a vaccine candidate against urinary schistosomiasisTranscriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKIIPraziquantel treatment decreases Schistosoma mansoni genetic diversity in experimental infectionsInhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to PraziquantelModulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel.Drug resistance in human helminths: current situation and lessons from livestockTowards an understanding of the mechanism of action of praziquantel.Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantelSchistosomiasis chemotherapy.Schistosome ABC multidrug transporters: From pharmacology to physiology.Chemotherapy for schistosomiasis in Ugandan fishermen: treatment can cause a rapid increase in interleukin-5 levels in plasma but decreased levels of eosinophilia and worm-specific immunoglobulin EIon channels and drug transporters as targets for anthelmintics.Pharmacology and potential physiological significance of schistosome multidrug resistance transportersVoltage-gated calcium channel subunits from platyhelminths: potential role in praziquantel action.Ca2+ signalling, voltage-gated Ca2+ channels and praziquantel in flatworm neuromusculature.Transcriptional analysis of Schistosoma mansoni treated with praziquantel in vitro.ABC multidrug transporters in schistosomes and other parasitic flatwormsNew approaches for understanding mechanisms of drug resistance in schistosomesAntischistosomal activity of a calcium channel antagonist on schistosomula and adult Schistosoma mansoni wormsNew insight into praziquantel against various developmental stages of schistosomes.Application of praziquantel in schistosomiasis japonica control strategies in China.Antiparasitic treatment of cerebral cysticercosis: lessons and experiences from China.New uses for old drugs: the tale of artemisinin derivatives in the elimination of schistosomiasis japonica in China.Genital schistosomiasis in women: a clinical 12-month in vivo study following treatment with praziquantel.Schistosome calcium channel beta subunits. Unusual modulatory effects and potential role in the action of the antischistosomal drug praziquantel.Treatment of Schistosoma mansoni with miltefosine in vitro enhances serological recognition of defined worm surface antigens.Senna leaf extracts induced Ca(+2) homeostasis in a zoonotic tapeworm Hymenolepis diminuta.Prospects for rational approaches to anthelmintic discovery.Schistosoma mansoni Ca2+-ATPase SMA2 restores viability to yeast Ca2+-ATPase-deficient strains and functions in calcineurin-mediated Ca2+ tolerance.How has the genomics era impacted schistosomiasis drug discovery?
P2860
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P2860
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Praziquantel: an urgent and exciting challenge.
@ast
Praziquantel: an urgent and exciting challenge.
@en
type
label
Praziquantel: an urgent and exciting challenge.
@ast
Praziquantel: an urgent and exciting challenge.
@en
prefLabel
Praziquantel: an urgent and exciting challenge.
@ast
Praziquantel: an urgent and exciting challenge.
@en
P2093
P1476
Praziquantel: an urgent and exciting challenge.
@en
P2093
Doenhoff MJ
Robertson A
P356
10.1016/0169-4758(96)80640-5
P577
1996-01-01T00:00:00Z