Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transpla
about
Prognostic significance of copy-number alterations in multiple myelomaDifferent Facets of Copy Number Changes: Permanent, Transient, and AdaptiveInterpretation of cytogenetic results in multiple myeloma for clinical practiceDrug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms.Advances in understanding prognosis in myeloma.Combining fluorescent in situ hybridization data with ISS staging improves risk assessment in myeloma: an International Myeloma Working Group collaborative project.Chromosome 1 amplification has similar prognostic value to del(17p13) and t(4;14)(p16;q32) in multiple myeloma patients: analysis of real-life data from the Polish Myeloma Study Group.Testing standard and genetic parameters in 220 patients with multiple myeloma with complete data sets: superiority of molecular genetics.Plasma cell leukemia.Metronomic therapy is an effective salvage treatment for heavily pre-treated relapsed/refractory multiple myelomaIdentification of novel antigens with induced immune response in monoclonal gammopathy of undetermined significance.p53 abnormalities and potential therapeutic targeting in multiple myeloma.Implications of heterogeneity in multiple myeloma.Input of DNA microarrays to identify novel mechanisms in multiple myeloma biology and therapeutic applications.CKS1B nuclear expression is inversely correlated with p27Kip1 expression and is predictive of an adverse survival in patients with multiple myelomaMinor clone provides a reservoir for relapse in multiple myelomaA critical role for the NFkB pathway in multiple myeloma.Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistanceMapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma.Cancer stem cells: controversies in multiple myelomaThe molecular classification of multiple myelomaPrognostic value and efficacy evaluation of novel drugs for cytogenetic aberrations in multiple myeloma: a meta-analysis.Retrospective analysis of genetic abnormalities and survival in 131 patients with multiple myeloma.Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocationsChromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients.Genetics of multiple myeloma: another heterogeneity level?Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total Therapy 3Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis.An intermediate-risk multiple myeloma subgroup is defined by sIL-6r: levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification.Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma.Progress in myeloma stem cellsCKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.Autologous Hematopoietic Stem Cell Transplantation in Dialysis-Dependent Myeloma Patients.Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myelomaA novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.Utilization of magnetic-activated cell sorting and high-density single nucleotide polymorphism microarrays improves diagnostic yield and prognostic value in clinical testing for patients with multiple myeloma and normal routine chromosome studyIn multiple myeloma, bone-marrow lymphocytes harboring the same chromosomal abnormalities as autologous plasma cells predict poor survivalGenetic events in the pathogenesis of multiple myeloma.
P2860
Q24643402-30A99BE9-5F74-4D25-8D9E-952FB122032CQ26769649-541DA9C5-7BAC-483E-A8F1-311079049685Q26777803-F4C0FA59-1F51-4051-B7A0-885DB00CAF5AQ27692033-C9C55785-1EBD-47EB-9117-957E5F7779D8Q30244061-32E3DC60-08B7-44CE-B583-6379D92C39E0Q30571858-C77FF3D7-CAB5-47CA-81CC-92E51ADF5230Q31154933-EBBCE572-3BBC-45C4-BF9B-3045626994BBQ33284138-9285D09B-0519-40F9-804E-ABA80586F770Q33393995-CCCE6A87-08A6-4CB5-8E5A-F0C8A2BAD321Q33408052-0318BD7C-0872-41F5-8BF9-7E2970903B66Q33479917-4DFFC6F4-5DED-4F05-BB0F-ED12C0C465C1Q33852683-AAA57628-0185-4FBD-8362-4F2CB2E73E65Q33914824-3FAF9986-BC3A-4824-A315-7CDA03DBB02FQ34022979-BE757364-00D8-410E-BF11-526E781884D4Q34095647-323222F2-A7AA-4B1B-98BF-1B148FDAB5BBQ34147170-19A5319E-B793-441B-9FC3-B532A05B3130Q34165181-D88650CF-F282-4FDB-90A8-35FABBDE9BE7Q34175179-E6F1BB6E-BC5A-4F31-A640-F4EEB13A7C8EQ34223730-22C005CE-4062-44A5-B1CC-E6DB177D8FF0Q34241661-8E9E8BEC-78FD-4A53-A5C6-F9FA9303877CQ34451553-54E7E134-CDFA-49FE-B7E7-0716AA527222Q34462722-42BACA4E-23DD-41C0-97F4-A064F2D34440Q34530992-FA56B27B-B6C8-46EF-A2AA-349CBE1E88CDQ34769841-CD8CAE62-0521-4977-A3CE-DFD4A86F3F7AQ34993904-77B3F000-1076-4376-B4D0-00FFFAF3EA85Q35081172-3CCC87A1-D029-4D72-9252-C474FF125436Q35125918-04C24A85-9300-4803-A009-9FDBAE6FF804Q35197437-7677FF7C-41AE-4E4E-89FF-D2F391F49832Q35266125-7629B794-FB23-4685-BD05-0CA427D678BFQ35628969-D942B87A-DE23-4673-8635-39D3148C3052Q35669234-7C0DA6FD-C953-41E7-B1A0-1391B144A0DFQ35724013-46C2A1A4-A7B3-4DC3-ACD6-95DFB32C9162Q35824980-544A8477-D165-42B3-9D74-3E989553D019Q35828815-D2326225-79A5-4E9A-B970-06080E9517FEQ35893993-CD639637-A0D4-4DA5-B3B8-02951BF18806Q35944699-4E29437D-8105-438F-82F8-D2A9764FA57BQ35984702-2D853796-C00A-497A-80CD-23056E3882C5Q36193269-7327BD4F-B60C-4D1A-B7DC-15E5145C6DA0Q36208638-DFD4305C-F8DA-4DDB-9946-CEB9E58D306DQ36380235-68AD6402-6260-4CAA-ADF0-5F50AF7DA930
P2860
Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transpla
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Frequent gain of chromosome ba ...... wing tandem stem-cell transpla
@ast
Frequent gain of chromosome ba ...... wing tandem stem-cell transpla
@en
type
label
Frequent gain of chromosome ba ...... wing tandem stem-cell transpla
@ast
Frequent gain of chromosome ba ...... wing tandem stem-cell transpla
@en
prefLabel
Frequent gain of chromosome ba ...... wing tandem stem-cell transpla
@ast
Frequent gain of chromosome ba ...... wing tandem stem-cell transpla
@en
P2093
P2860
P1433
P1476
Frequent gain of chromosome ba ...... wing tandem stem-cell transpla
@en
P2093
Bart Burington
Federica Cavallo
Fenghuang Zhan
Guido Tricot
Ichiro Hanamura
James P Stewart
Jeffrey R Sawyer
John Crowley
John D Shaughnessy
Klaus Hollmig
P2860
P304
P356
10.1182/BLOOD-2006-03-009910
P407
P577
2006-05-16T00:00:00Z