Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4 - Wikidata - awgldk - TriplyDB

Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

http://www.wikidata.org/entity/Q35849667

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Common stemness regulators of embryonic and cancer stem cells Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells Recent developments in β-cell differentiation of pluripotent stem cells induced by small and large molecules Ex uno plures: molecular designs for embryonic pluripotency Changes in human pluripotent stem cell gene expression after genotoxic stress exposures Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes.Molecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency network Dickkopf Wnt signaling pathway inhibitor 1 regulates the differentiation of mouse embryonic stem cells in vitro and in vivo WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling Efficient and rapid induction of human iPSCs/ESCs into nephrogenic intermediate mesoderm using small molecule-based differentiation methods Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States Wnt-YAP interactions in the neural fate of human pluripotent stem cells and the implications for neural organoid formation The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice Technology advancement for integrative stem cell analyses Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells.Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling.New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells.Gene expression profile in human induced pluripotent stem cells: Chondrogenic differentiation in vitro, part A Primate embryogenesis predicts the hallmarks of human naïve pluripotency.Developmental insights from early mammalian embryos and core signaling pathways that influence human pluripotent cell growth and differentiation.Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling.Clinical significance of POU5F1P1 rs10505477 polymorphism in Chinese gastric cancer patients receving cisplatin-based chemotherapy after surgical resection.Protein kinase C-induced early growth response protein-1 binding to SNAIL promoter in epithelial-mesenchymal transition of human embryonic stem cells.Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal.The self-renewal of mouse embryonic stem cells is regulated by cell-substratum adhesion and cell spreading IFNγ-induced suppression of β-catenin signaling: evidence for roles of Akt and 14.3.3ζ.Involvement of crosstalk between Oct4 and Meis1a in neural cell fate decision.A small molecule inhibitor of SRC family kinases promotes simple epithelial differentiation of human pluripotent stem cells.Wnt signaling and the control of human stem cell fate.β-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells Epiblast ground state is controlled by canonical Wnt/β-catenin signaling in the postimplantation mouse embryo and epiblast stem cells.Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma.A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cells GSK3 inhibitors CHIR99021 and 6-bromoindirubin-3'-oxime inhibit microRNA maturation in mouse embryonic stem cells On human pluripotent stem cell control: The rise of 3D bioengineering and mechanobiology.Nanog down-regulates the Wnt signaling pathway via β-catenin phosphorylation during epidermal stem cell proliferation and differentiation.Application Of Small Molecules Favoring Naïve Pluripotency during Human Embryonic Stem Cell Derivation.CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells.Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling.Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells.

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P2860

Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

http://www.wikidata.org/entity/Q35849667

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Wnt/β-catenin signaling promot ...... cells and is repressed by Oct4

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Wnt/β-catenin signaling promot ...... cells and is repressed by Oct4

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Wnt/β-catenin signaling promot ...... cells and is repressed by Oct4

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Wnt/β-catenin signaling promot ...... cells and is repressed by Oct4

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Wnt/β-catenin signaling promot ...... cells and is repressed by Oct4

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Wnt/β-catenin signaling promot ...... cells and is repressed by Oct4

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Wnt/β-catenin signaling promot ...... cells and is repressed by Oct4

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Allison M Adams

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Circe E McDonald

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Jason D Berndt

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Jennifer C Potter

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Kathryn C Davidson

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Russell J Taylor

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Travis L Biechele

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P2860

ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Wnt/beta-catenin signaling in development and disease

Nanog and transcriptional networks in embryonic stem cell pluripotency

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

Wnt signaling promotes reprogramming of somatic cells to pluripotency

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

Derivation of pluripotent epiblast stem cells from mammalian embryos

New cell lines from mouse epiblast share defining features with human embryonic stem cells

Transcriptional analysis of early lineage commitment in human embryonic stem cells

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Randall T. Moon

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