Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures. - Wikidata - awgldk - TriplyDB

Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.

Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.

http://www.wikidata.org/entity/Q35850108

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Cyclooxygenase- and cytochrome P450-derived eicosanoids in stroke Mesenchymal stem cells with overexpression of midkine enhance cell survival and attenuate cardiac dysfunction in a rat model of myocardial infarction.Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor Additive Neuroprotection of a 20-HETE Inhibitor with Delayed Therapeutic Hypothermia after Hypoxia-Ischemia in Neonatal Piglets Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target P450 Eicosanoids and Reactive Oxygen Species Interplay in Brain Injury and Neuroprotection.GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses Cytochrome P450 eicosanoids in cerebrovascular function and disease.Expression of CYP 4A ω-hydroxylase and formation of 20-hydroxyeicosatetreanoic acid (20-HETE) in cultured rat brain astrocytes.Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with 11C-labeled 20-HETE synthase-specific inhibitor.Effects of Gualou Guizhi Decoction Aqueous Extract on Axonal Regeneration in Organotypic Cortical Slice Culture after Oxygen-Glucose Deprivation.20-Hydroxyeicosatetraenoic Acid Inhibition by HET0016 Offers Neuroprotection, Decreases Edema, and Increases Cortical Cerebral Blood Flow in a Pediatric Asphyxial Cardiac Arrest Model in Rats.Upregulation of 20-HETE Synthetic Cytochrome P450 Isoforms by Oxygen-Glucose Deprivation in Cortical Neurons.Cerebral Autoregulation in Hypertension and Ischemic Stroke: A Mini Review

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P2860

Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.

http://www.wikidata.org/entity/Q35850108

description

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AJPHEART.00340.2011

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American Journal of Physiology - Heart and Circulatory Physiology

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Protective effect of 20-HETE i ...... in hippocampal slice cultures

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David R Harder

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Debebe Gebremedhin

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Marija Renic

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Matthew A Florence

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Nashaat Z Gerges

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Richard J Roman

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Suresh N Kumar

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P2860

HET0016, a potent and selective inhibitor of 20-HETE synthesizing enzyme

A simple method for organotypic cultures of nervous tissue

Spatiotemporal evidence of apoptosis-mediated ischemic injury in organotypic hippocampal slice cultures.

Ionotropic glutamate receptors and glutamate transporters are involved in necrotic neuronal cell death induced by oxygen-glucose deprivation of hippocampal slice cultures.

Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia.

Effect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion.

Reactive oxygen radicals in signaling and damage in the ischemic brain.

20-Hydroxyeicosatetraenoic acid induces apoptosis in neonatal rat cardiomyocytes through mitochondrial-dependent pathways.

Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation.

20-hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling.

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