Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. - Wikidata - awgldk - TriplyDB

Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells.

Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells.

http://www.wikidata.org/entity/Q35851748

about

Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression Tumor-intrinsic oncogene pathways mediating immune avoidance Signaling in T cells - is anything the m(a)TOR with the picture(s)?Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy Tumor-infiltrating dendritic cells in cancer pathogenesis Dendritic cells: arbiters of immunity and immunological tolerance In Vivo Visualization of Tumor Antigen-containing Microparticles Generated in Fluorescent-protein-elicited Immunity.Real-Time Imaging of Resident T Cells in Human Lung and Ovarian Carcinomas Reveals How Different Tumor Microenvironments Control T Lymphocyte Migration Genetically engineered mouse models in oncology research and cancer medicine Oxidized lipids block antigen cross-presentation by dendritic cells in cancer Intravital Microscopy Imaging Approaches for Image-Guided Drug Delivery Systems CD8+ tumor-infiltrating T cells are trapped in the tumor-dendritic cell network.An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations.Intravital and whole-organ imaging reveals capture of melanoma-derived antigen by lymph node subcapsular macrophages leading to widespread deposition on follicular dendritic cells.Tumor-infiltrating lymphocytes are dynamically desensitized to antigen but are maintained by homeostatic cytokine.Development of novel murine mammary imaging windows to examine wound healing effects on leukocyte trafficking in mammary tumors with intravital imaging.Critical Role for CD103(+)/CD141(+) Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma.CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models.The cellular and molecular origin of tumor-associated macrophages.Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects The emerging understanding of myeloid cells as partners and targets in tumor rejection.Cervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretion.Intratumoral dendritic cells in the anti-tumor immune response Tumor and Host Factors Controlling Antitumor Immunity and Efficacy of Cancer Immunotherapy.Adaptive Immune Regulation of Mammary Postnatal Organogenesis Directing the assembly of spatially organized multicomponent tissues from the bottom up.Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response.PD-1 Blunts the Function of Ovarian Tumor-Infiltrating Dendritic Cells by Inactivating NF-κB An evolutionary perspective on anti-tumor immunity Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis.Live imaging of drug responses in the tumor microenvironment in mouse models of breast cancer.Role of dendritic cells in the regulation of antitumor immunity Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment.Genetically engineered mouse models of cancer reveal new insights about the antitumor immune response.T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro.Instruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations.

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P2860

Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells.

http://www.wikidata.org/entity/Q35851748

description

2012 nî lūn-bûn

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J.CCR.2012.01.008

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P2093

Caitlin Sorensen

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John J Engelhardt

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Matthew F Krummel

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Priya Pandurangi

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Zena Werb

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P2860

Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor

A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma

Adoptive immunotherapy for cancer: building on success

Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

Myeloid-derived suppressor cells as regulators of the immune system

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

Two-photon imaging of lymphocyte motility and antigen response in intact lymph node

Macrophage diversity enhances tumor progression and metastasis

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402-417

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Peter Beemiller

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221968771

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3311997

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