Biologically active sphingolipids in cancer pathogenesis and treatment.
about
Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignanciesStress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processingProteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosisSphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramideThe sphingolipid salvage pathway in ceramide metabolism and signalingIdentification of aberrant forms of alkaline sphingomyelinase (NPP7) associated with human liver tumorigenesisRoles of bioactive sphingolipids in cancer biology and therapeuticsLASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificityComparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines.Emerging role of sphingosine-1-phosphate signaling in head and neck squamous cell carcinomaTrafficking and Functions of Bioactive Sphingolipids: Lessons from Cells and Model MembranesA novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosisSphingosine kinase 1/sphingosine 1-phosphate signalling pathway as a potential therapeutic target of pulmonary hypertensionTargeting chronic lymphocytic leukemia cells in the tumor microenviroment: A review of the in vitro and clinical trials to dateAutophagy paradox and ceramideAdipocytes: impact on tumor growth and potential sites for therapeutic interventionPlant sterols as anticancer nutrients: evidence for their role in breast cancerNanoparticle-based targeted therapeutics in head-and-neck cancerNeutral sphingomyelinase and breast cancer researchA review of ceramide analogs as potential anticancer agentsExport of sphingosine-1-phosphate and cancer progressionOn ceramides, other sphingolipids and impaired glucose homeostasisRoles and regulation of neutral sphingomyelinase-2 in cellular and pathological processesElisidepsin Interacts Directly with Glycosylceramides in the Plasma Membrane of Tumor Cells to Induce Necrotic Cell DeathCrystal structure of YegS, a homologue to the mammalian diacylglycerol kinases, reveals a novel regulatory metal binding siteRegulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1Ceramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid LeukemiaClients and Oncogenic Roles of Molecular Chaperone gp96/grp94Cell membrane modulation as adjuvant in cancer therapyRole of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in HumansStress responses from the endoplasmic reticulum in cancerBioactive lipids and the control of Bax pro-apoptotic activityA human memory T cell subset with stem cell-like propertiesThe multigenic sphingomyelin synthase familyMolecular requirements for doxorubicin-mediated death in murine oocytesCeramide induced mitophagy and tumor suppressionA new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosisMitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant miceCeramide Synthase 6 Is a Novel Target of Methotrexate Mediating Its Antiproliferative Effect in a p53-Dependent MannerCalcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis
P2860
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P2860
Biologically active sphingolipids in cancer pathogenesis and treatment.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Biologically active sphingolipids in cancer pathogenesis and treatment.
@ast
Biologically active sphingolipids in cancer pathogenesis and treatment.
@en
type
label
Biologically active sphingolipids in cancer pathogenesis and treatment.
@ast
Biologically active sphingolipids in cancer pathogenesis and treatment.
@en
prefLabel
Biologically active sphingolipids in cancer pathogenesis and treatment.
@ast
Biologically active sphingolipids in cancer pathogenesis and treatment.
@en
P356
P1476
Biologically active sphingolipids in cancer pathogenesis and treatment.
@en
P2093
Besim Ogretmen
Yusuf A Hannun
P2888
P304
P356
10.1038/NRC1411
P407
P577
2004-08-01T00:00:00Z