Mitochondria and dopamine: new insights into recessive parkinsonism.
about
RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolismMutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stabilityMutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal deathMolecules that cause or prevent Parkinson's diseaseExclusion of PINK1 as candidate gene for the late-onset form of Parkinson's disease in two European populations.Multimodal MRI Evaluation of the MitoPark Mouse Model of Parkinson's DiseasePro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteinsLoss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stressMitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by ParkinNeuroproteomics as a promising tool in Parkinson's disease research.Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling.Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's diseaseLoss of DJ-1 does not affect mitochondrial respiration but increases ROS production and mitochondrial permeability transition pore openingDrosophila models of neurodegenerative diseases.Deep Imaging: the next frontier in microscopy.Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neuronsEnhanced J-protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's diseaseCell systems and the toxic mechanism(s) of alpha-synucleinMitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat.Complexity of dopamine metabolism.Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(-/-) mice.Molecular pathology of Lewy body diseases.Antioxidant SkQ1 delays sarcopenia-associated damage of mitochondrial ultrastructure.Oxidative Modification and Its Implications for the Neurodegeneration of Parkinson's Disease.alpha-synuclein and LRRK2: partners in crime.Parkinson's disease: genetics and beyond.Impaired neurotransmitter release in Alzheimer's and Parkinson's diseases.Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress.Understanding and treating neurodegeneration: insights from the flies.Syndromic approach to Parkinson's disease: role of functional imaging.Dissembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients.PARK14 PLA2G6 mutants are defective in preventing rotenone-induced mitochondrial dysfunction, ROS generation and activation of mitochondrial apoptotic pathway.Subtle alterations of excitatory transmission are linked to presynaptic changes in the hippocampus of PINK1-deficient mice.PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism.A New Treatment Strategy for Parkinson's Disease through the Gut-Brain Axis: The Glucagon-Like Peptide-1 Receptor Pathway.
P2860
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P2860
Mitochondria and dopamine: new insights into recessive parkinsonism.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Mitochondria and dopamine: new insights into recessive parkinsonism.
@ast
Mitochondria and dopamine: new insights into recessive parkinsonism.
@en
type
label
Mitochondria and dopamine: new insights into recessive parkinsonism.
@ast
Mitochondria and dopamine: new insights into recessive parkinsonism.
@en
prefLabel
Mitochondria and dopamine: new insights into recessive parkinsonism.
@ast
Mitochondria and dopamine: new insights into recessive parkinsonism.
@en
P1433
P1476
Mitochondria and dopamine: new insights into recessive parkinsonism.
@en
P2093
P304
P356
10.1016/J.NEURON.2004.07.012
P407
P577
2004-08-01T00:00:00Z