High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.
about
Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and CancerMapping paths: new approaches to dissect eukaryotic signaling circuitryTRAPP Complexes in Secretion and AutophagyAdaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbationsCRISPR-Cas9: from Genome Editing to Cancer ResearchCRISPR guide RNA design for research applicationsAccelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screeningPooled-matrix protein interaction screens using Barcode Fusion GeneticsTwo Distinct Types of E3 Ligases Work in Unison to Regulate Substrate UbiquitylationIdentification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screeningThe BioGRID interaction database: 2017 updateOGEE v2: an update of the online gene essentiality database with special focus on differentially essential genes in human cancer cell linesA CRISPR toolbox to study virus-host interactionsGenomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2.A novel RNA sequencing data analysis method for cell line authentication.CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.Synthetic lethality: emerging targets and opportunities in melanoma.Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screensSerotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts.CRISPR/Cas9: From Genome Engineering to Cancer Drug DiscoveryFlexible CRISPR library construction using parallel oligonucleotide retrieval.A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes.Induced Pluripotent Stem Cells Meet Genome EditingApplications of CRISPR technologies in research and beyond.A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.BAGEL: a computational framework for identifying essential genes from pooled library screens.Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9.Genome-scale CRISPR pooled screens.Practical Considerations for Using Pooled Lentiviral CRISPR Libraries.Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.Increasing the performance of pooled CRISPR-Cas9 drop-out screening.Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor EvolutionValidation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening.sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity.Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.Scalable Design of Paired CRISPR Guide RNAs for Genomic DeletionTissue-specific tumorigenesis: context matters.Functional interrogation of non-coding DNA through CRISPR genome editing.
P2860
Q26738712-22153C2B-F5F2-4798-A025-A727E9F5130BQ26740311-3133E83D-6AD6-42FF-BCD9-308C6BE530D4Q26749341-94BA38C9-248D-4666-8998-3BD1A0BFFAEDQ26765956-7688EC7B-BE9A-4033-A1D0-21C399BDEEC0Q28066263-389C1E5F-3813-4A7F-8A2D-0C406043030FQ28075898-01CB0823-B311-440C-8951-39D3483560F1Q28080068-F4E352AB-C535-422A-BEF9-4ECD8E4EEA78Q28114947-50FB601A-8699-480A-BFBE-34970B85AF2CQ28115944-61422E94-F6F3-40D2-B67C-8B23643720ABQ28596034-01FAB3C1-1F4E-4F1E-AFEB-663975B90E32Q28818109-E49C2C8B-6DA2-46B0-9EA2-FF848D3B82BEQ28818119-ADD3B484-8354-4583-A7CD-05169802173BQ29994612-20186520-F4D5-4BB8-B449-5A3A19E38CF7Q30399258-B738FC70-6F23-42FB-8EE4-8EE62A9327A3Q31161522-E866D79D-1DB1-4643-B66B-615BA3F510F0Q33573686-23609468-79B6-4653-B43A-47F52801FB18Q33578398-B66BABDD-64E6-4E14-933D-059D0E990240Q33654299-6B4CD3B2-2C75-4D72-9BD2-5B9B07099F32Q33762032-B16397EE-F38A-40C4-B93F-7F8B469BD538Q33772342-EB172E48-9EBA-4ACE-A4F2-FA59FF9BD005Q33879061-36B79318-59CE-41B5-A6D8-3ACE942A318FQ33906477-FA250198-B41F-4F12-9AF7-8F37811DB1A5Q34046778-296328C6-B99F-4D51-87FE-8C13D3799594Q34525438-E516A299-EE4B-466A-9BC9-5BC889D96C27Q34539796-60A1E5CA-9BCC-4B07-988A-E88798D14B2FQ34543038-287B72C2-A34D-4863-9632-D50FE121CA9DQ35991327-A995E401-770B-4FC9-B9CE-9BDD5F33E5DAQ36011163-0FDF9431-4A89-4ACC-B644-7E59CF851D06Q36040827-168A56E9-AAEB-4CFF-A2EE-2EE11ABD7A1BQ36065701-AB1A7E72-F769-45CF-92ED-514BDB378F04Q36068445-02AAF217-830A-4D5C-BC66-2C263ECA9C0FQ36108527-7A7497E2-C5A0-4E35-9570-F764785FE287Q36142402-C6DC9E9D-B841-4EA4-883A-8B13948AC861Q36233887-71F56CB9-6C29-472C-B232-CDD9050975D5Q36234911-C0CA5758-F981-4766-ADB6-8E6BB40CED0BQ36266204-8F735031-2DB0-45DC-BB89-6F65BDAD84A4Q36282203-7957C01B-AC54-46D5-916C-3B06B18FE953Q36295173-A3B8B647-BB38-4A11-8D6A-5786C812A72EQ36296335-57624402-81C6-4C31-A2A7-CE7B97741C4AQ36306820-458C9D2D-66D1-4C80-BC50-6F472BD074FF
P2860
High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.
@ast
High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.
@en
type
label
High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.
@ast
High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.
@en
prefLabel
High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.
@ast
High-Resolution CRISPR Screens ...... e-Specific Cancer Liabilities.
@en
P2093
P50
P1433
P1476
High-Resolution CRISPR Screens ...... pe-Specific Cancer Liabilities
@en
P2093
Daniel Durocher
Graham MacLeod
Kevin R Brown
Megha Chandrashekhar
Michal Zimmermann
Monika Mis
Olivia S Rissland
Patricia Mero
Peter Dirks
Sachdev Sidhu
P304
P356
10.1016/J.CELL.2015.11.015
P407
P577
2015-11-25T00:00:00Z