Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
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High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticityExercise interventions for preventing dementia or delaying cognitive decline in people with mild cognitive impairmentExercise interventions for maintaining cognitive function in cognitively healthy people in mid lifeExercise interventions for maintaining cognitive function in cognitively healthy people in late lifeIntranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidenceHow insulin engages its primary binding site on the insulin receptorBrain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in HumansTherapies for Prevention and Treatment of Alzheimer's DiseaseThe Rationale for Insulin Therapy in Alzheimer's DiseaseComplex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunctionDegeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson's DiseaseRedox Imbalance and Viral Infections in Neurodegenerative DiseasesThe association between PGC-1α and Alzheimer's diseaseInflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's DiseasePotentials of incretin-based therapies in dementia and stroke in type 2 diabetes mellitusMolecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisalMetabolic Alterations Associated to Brain Dysfunction in DiabetesShared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer's Disease: Impacts on Cognitive DeclineThe impact of hippocampal lesions on trace-eyeblink conditioning and forebrain-cerebellar interactionsMolecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β-Cell DysfunctionDietary advanced glycation end products and their role in health and diseaseCerebral energy metabolism and the brain's functional network architecture: an integrative reviewIntranasal insulin therapy for cognitive impairment and neurodegeneration: current state of the artLink between type 2 diabetes and Alzheimer's disease: from epidemiology to mechanism and treatmentCommon defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploringThe impairment of insulin signaling in Alzheimer's diseaseMetabolic actions of Rho-kinase in periphery and brainNew drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseasesInsulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's diseaseAlzheimer's disease and insulin resistance: translating basic science into clinical applicationsElevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brainInconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's diseaseInsulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndromeFood for thought: the role of appetitive peptides in age-related cognitive declineBrain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogsRoles of vascular and metabolic components in cognitive dysfunction of Alzheimer disease: short- and long-term modification by non-genetic risk factorsAberrant insulin signaling in Alzheimer's disease: current knowledgeMetformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathyHigh-fat diet impairs spatial memory and hippocampal intrinsic excitability and sex-dependently alters circulating insulin and hippocampal insulin sensitivityNeuropathology of type 2 diabetes: a short review on insulin-related mechanisms
P2860
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P2860
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Demonstrated brain insulin res ...... lation, and cognitive decline.
@ast
Demonstrated brain insulin res ...... lation, and cognitive decline.
@en
type
label
Demonstrated brain insulin res ...... lation, and cognitive decline.
@ast
Demonstrated brain insulin res ...... lation, and cognitive decline.
@en
prefLabel
Demonstrated brain insulin res ...... lation, and cognitive decline.
@ast
Demonstrated brain insulin res ...... lation, and cognitive decline.
@en
P2093
P2860
P50
P356
P1476
Demonstrated brain insulin res ...... lation, and cognitive decline.
@en
P2093
Andres Stucky
Andrew J Samoyedny
Bryan A Wolf
Hoau-Yan Wang
Julie A Schneider
Kalindi P Bakshi
Konrad Talbot
Krista R Kawaguchi
Li-Ying Han
P2860
P304
P356
10.1172/JCI59903
P407
P577
2012-04-01T00:00:00Z